About this Research Topic
More and more attention has been paid to multi-omics research, and single-target treatment of tumors has become the past. In the future, the frontier trend of this field at home and abroad is multi-target, multi-pathway, and even multi-disciplinary combined treatment. Including, but not limited to, epigenetic regulation of digestive system tumors, non-coding RNA roles in digestive system tumors, cancer stem cells in digestive system tumors, genetic risk factors of digestive system tumors, chromosome, gene, DNA variation and microenvironment genetics of digestive system tumors, targeted therapy of digestive system tumors, pharmacogenetics for optimizing the treatment of digestive system tumors, biomarkers and immunotherapy of digestive system tumors, etc.
The original research and review papers focusing on, but not limited to, the following:
• Somatic genomic variants in digestive system tumors
• Microenvironment, molecular analysis in digestive system tumors
• To analyze the cancer subtypes of digestive system tumors and predict the prognosis of cancer based on artificial intelligence multi-omics
• Epigenetic changes and the signal interaction mechanisms in the development of digestive system tumors
• To identify the key target genes or signaling pathways of digestive system tumors, and to explore their potential mechanisms for the prevention and treatment of metastasis and drug resistance of digestive system tumors
• Target discovery and testing for small-molecule drugs
• New tumor imaging probes, molecular imaging, PET imaging probes and other diagnostic strategies
Keywords: digestive system carcinoma, molecular diagnosis, molecular pathogenesis, targeted therapy, tumorigenesis
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