Organic Chemical Synthesis is a rapidly evolving field that has seen significant advancements in recent years. The continuous development of new synthetic methodologies, catalysts, and reaction mechanisms has propelled the field forward, enabling the synthesis of complex molecules with high precision and efficiency. Despite these advancements, several challenges remain, including the need for more sustainable and environmentally friendly synthetic processes, the development of more selective and efficient catalysts, and the synthesis of increasingly complex natural products and pharmaceuticals. Recent studies have highlighted the potential of novel catalytic systems, such as organ catalysts and transition metal catalysts, in addressing some of these challenges. However, there is still a need for a deeper understanding of reaction mechanisms and the development of new strategies to overcome existing limitations.

This research topic aims to provide a comprehensive overview of the latest advancements and future challenges in the field of Organic Chemical Synthesis. The main objectives are to highlight recent developments, identify the greatest challenges in the sub-disciplines, and propose potential solutions to address these challenges. Specific questions to be answered include: What are the most promising new synthetic methodologies? How can we develop more sustainable and efficient synthetic processes? What are the latest advancements in catalyst design and reaction mechanisms? By addressing these questions, this research topic seeks to inspire and inform researchers, providing direction and guidance for future research in the field.

To gather further insights in the field of Organic Chemical Synthesis, we welcome articles addressing, but not limited to, the following themes:
- Development of new synthetic methodologies
- Advances in catalyst design and reaction mechanisms
- Sustainable and environmentally friendly synthetic processes
- Synthesis of complex natural products and pharmaceuticals
- Applications of organic synthesis in chemical biology
- Computational approaches in organic synthesis
- Challenges and future perspectives in organic chemical synthesis

This collection aims to provide a thorough overview of the field, highlighting recent achievements and identifying future directions for research.

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Frontiers in Chemical Biology

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