About this Research Topic
The field of skeletal muscle wasting encompasses systemic and local alterations including inflammation and distinct circulating biomarkers. Skeletal muscle possesses the unique ability to synthesize and secrete proteins with signaling capabilities, which are crucial for managing changes in muscle mass prompted by factors such as nutritional intake, physical activity, and medical treatments. Identifying these biomarkers plays a pivotal role in understanding skeletal muscle signaling pathways, which could significantly mitigate muscle degradation in conditions like cancer, aging, and various muscle disorders.
This Research Topic aims to deepen the understanding of skeletal muscle wasting by exploring its systemic markers and their modulation through therapeutic strategies. We seek to uncover how these biomarkers interact with muscle signaling processes and the potential interventions to alleviate muscle loss.
To gather further insights into the intricate dynamics of skeletal muscle biology, we welcome articles addressing, but not limited to, the following themes:
• Identification of biomarkers of skeletal muscle wasting.
• Clinical or translational signaling pathways associated with muscle wasting.
• Impact of dietary strategies, supplements, pharmacological treatments, and exercise regimens on skeletal muscle wasting.
Through these inquiries, the Research Topic hopes to uncover novel therapeutic avenues that could prevent or reverse muscle wasting, providing significant benefits in clinical settings and improving patient outcomes.
Keywords: #CollectionSeries, Sarcopenia, Cachexia, Skeletal Muscle, Inflammation, Myokines, Cytokines, Muscle Wasting
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.