Ultrasound has long been utilized as a diagnostic tool in various medical applications. Recent advancements have expanded its potential for brain applications, including neuromodulation, neuroimaging, drug delivery, brain therapy, and therapy monitoring. Ultrasound technology offers several advantages over traditional methods, such as non-invasiveness, real-time monitoring, and precise targeting. These advancements have opened up new possibilities for understanding and treating neurological disorders. The use of ultrasound for brain applications involves the development of specialized devices, transducers, and acoustic materials. These components play a crucial role in delivering focused ultrasound waves to specific regions of the brain with high precision and minimal side effects. Innovative transducer designs and improved acoustic materials have emerged to enhance the efficiency and safety of ultrasound-based brain interventions. Moreover, the integration of imaging techniques with ultrasound has enabled real-time visualization of brain structures and improved targeting accuracy.

The goal of this research topic is to explore the latest developments in ultrasound technology and devices for brain applications. The specific problem we aim to tackle is how to enhance the effectiveness and safety of various brain interventions, such as neuromodulation, neuroimaging, drug delivery, brain therapy, and therapy monitoring. We encourage contributors to address the challenges associated with these applications and propose novel approaches to overcome them.

Specifically, we encourage contributors to address the following themes within this scope:
(1) neuromodulation techniques utilizing ultrasound for non-invasive brain stimulation,

(2) innovative ultrasound-based neuroimaging methods for enhanced visualization and characterization of brain structures,

(3) novel approaches in ultrasound-mediated drug delivery to the brain for targeted therapy,

(4) the development and optimization of ultrasound devices and techniques for brain therapy, and

(5) monitoring and assessment of therapy outcomes using ultrasound-based imaging and sensing modalities.

We welcome original research articles, reviews, and methodological papers that explore these themes and provide insights into recent advances, challenges, and future directions in ultrasound technology for brain applications. The scope also includes studies that demonstrate the integration of ultrasound with other imaging modalities or technologies to achieve synergistic effects in brain interventions. By bringing together multidisciplinary research, this Research Topic aims to foster collaboration with neuroscience and drive further innovation in ultrasound-based approaches for the brain.

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Frontiers in Neuroscience

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