Recent research has highlighted the importance of the human microbiome in health and disease, yet the role of the skin microbiome in allergic skin diseases such as atopic dermatitis, allergic contact dermatitis, and urticaria, remains unclear. The skin microbiome is a complex ecosystem, comprising diverse microorganisms that interact with the host immune system, potentially influencing the skin's barrier function, inflammation, and immune response. Thus, a comprehensive investigation into the skin microbiome's composition and function in allergic skin diseases could offer valuable insights into the pathogenesis of these conditions and reveal potential therapeutic targets.
The goal of this research topic is to address current knowledge gaps in understanding the role of the skin microbiome in allergic skin diseases, such as atopic dermatitis, allergic contact dermatitis, and urticaria. By investigating the composition and function of the skin microbiome and its interaction with the host immune system, this research topic aims to identify the mechanisms underlying the pathogenesis of these diseases and identify potential therapeutic targets. Ultimately, this research may lead to the development of novel therapies that can modulate the skin microbiome to prevent or treat allergic skin diseases.
Research Question: What is the composition and function of the skin microbiome in allergic skin diseases, and how does it interact with the host immune system?
This research topic welcomes a multi-omics approach to characterize the composition and function of the skin microbiome in patients with allergic skin diseases. Authors may wish to explore the skin microbiome's functional capacity and interaction with the host immune system. This research topic should consider the impact of different factors such as age, sex, genetics, environment, and treatment on the skin microbiome's composition and function.
This research topic will provide a comprehensive understanding of the skin microbiome's role in allergic skin diseases and its interaction with the host immune system. Findings may inform the development of probiotic or prebiotic interventions that could modulate the skin microbiome and improve disease outcomes and/or lead to the identification of novel therapeutic targets for these diseases and pave the way for personalized medicine approaches.
Unravelling the Role of the Skin Microbiome in Allergic Skin Diseases is a broad research topic and encompasses several sub-themes that authors can consider, including:
1. Characterization of the skin microbiome in allergic skin diseases
2. Dysbiosis of the skin microbiome and allergic skin diseases
3. Interactions between the skin microbiome and host immune system in allergic skin diseases
4. The impact of environmental factors on the skin microbiome in allergic skin diseases
5. Microbiome-targeted therapies for allergic skin diseases
6. The role of prebiotics, probiotics, and postbiotics in modulating the skin microbiome in allergic skin diseases
7. Microbiome-based biomarkers for diagnosis and prognosis of allergic skin diseases
8. The influence of lifestyle factors on the skin microbiome in allergic skin diseases
9. The relationship between the gut microbiome and the skin microbiome in allergic skin diseases
10. The role of skin microbiome transplantation in the management of allergic skin diseases
Keywords:
Skin microbiome; Allergic skin diseases; Atopic dermatitis; Immune response; Therapeutic targets
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Recent research has highlighted the importance of the human microbiome in health and disease, yet the role of the skin microbiome in allergic skin diseases such as atopic dermatitis, allergic contact dermatitis, and urticaria, remains unclear. The skin microbiome is a complex ecosystem, comprising diverse microorganisms that interact with the host immune system, potentially influencing the skin's barrier function, inflammation, and immune response. Thus, a comprehensive investigation into the skin microbiome's composition and function in allergic skin diseases could offer valuable insights into the pathogenesis of these conditions and reveal potential therapeutic targets.
The goal of this research topic is to address current knowledge gaps in understanding the role of the skin microbiome in allergic skin diseases, such as atopic dermatitis, allergic contact dermatitis, and urticaria. By investigating the composition and function of the skin microbiome and its interaction with the host immune system, this research topic aims to identify the mechanisms underlying the pathogenesis of these diseases and identify potential therapeutic targets. Ultimately, this research may lead to the development of novel therapies that can modulate the skin microbiome to prevent or treat allergic skin diseases.
Research Question: What is the composition and function of the skin microbiome in allergic skin diseases, and how does it interact with the host immune system?
This research topic welcomes a multi-omics approach to characterize the composition and function of the skin microbiome in patients with allergic skin diseases. Authors may wish to explore the skin microbiome's functional capacity and interaction with the host immune system. This research topic should consider the impact of different factors such as age, sex, genetics, environment, and treatment on the skin microbiome's composition and function.
This research topic will provide a comprehensive understanding of the skin microbiome's role in allergic skin diseases and its interaction with the host immune system. Findings may inform the development of probiotic or prebiotic interventions that could modulate the skin microbiome and improve disease outcomes and/or lead to the identification of novel therapeutic targets for these diseases and pave the way for personalized medicine approaches.
Unravelling the Role of the Skin Microbiome in Allergic Skin Diseases is a broad research topic and encompasses several sub-themes that authors can consider, including:
1. Characterization of the skin microbiome in allergic skin diseases
2. Dysbiosis of the skin microbiome and allergic skin diseases
3. Interactions between the skin microbiome and host immune system in allergic skin diseases
4. The impact of environmental factors on the skin microbiome in allergic skin diseases
5. Microbiome-targeted therapies for allergic skin diseases
6. The role of prebiotics, probiotics, and postbiotics in modulating the skin microbiome in allergic skin diseases
7. Microbiome-based biomarkers for diagnosis and prognosis of allergic skin diseases
8. The influence of lifestyle factors on the skin microbiome in allergic skin diseases
9. The relationship between the gut microbiome and the skin microbiome in allergic skin diseases
10. The role of skin microbiome transplantation in the management of allergic skin diseases
Keywords:
Skin microbiome; Allergic skin diseases; Atopic dermatitis; Immune response; Therapeutic targets
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.