Neurological and oncological intersections are increasingly relevant in medical research due to rising survival rates from cancer, which inadvertently elevate the risk of associated complications such as strokes. Approximately one in ten ischemic stroke victims also suffer from concurrent cancer, a statistic anticipated to increase with the advancements in cancer treatments that prolong survival. Recent studies reveal an emergence of stroke within two years of a cancer diagnosis in an additional 3-5% of cases. These include strokes that coincide with specific cancer therapies like chemotherapy and radiation, which could augment stroke risk through various mechanisms including the induction of hypercoagulable states. Moreover, certain cancers have shown a high propensity to cause vascular complications, thus exacerbating the likelihood of stroke.

This Research Topic aims to collate and synthesize comprehensive data on the prevalence, prognosis, and predictors of stroke in cancer patients, constituting a subgroup with unique clinical challenges. Understanding the bi-directional influences of cancer and stroke, particularly the epidemiological patterns and underlying pathophysiological mechanisms, is crucial. It seeks to delineate the factors that predict stroke occurrence in cancer patients, examining both direct and indirect influences like coagulopathies and infection-driven risks. Furthermore, it aims to examine the effectiveness of various stroke prevention and management strategies in this vulnerable population, emphasizing the need for adapted clinical protocols that accommodate the intricate needs of patients suffering concurrently from cancer and stroke.

To gather further insights concerning the interplay between these two serious health conditions, we welcome the submission of any type of manuscript supported by the journal that focus on, but are not limited to, the following themes:
• Prevalence, incidence, and mortality of stroke among individuals with cancer
• Impact of chemotherapy and radiotherapy on stroke risk
• Shared risk factors between ischemic strokes and oncological conditions
• Pathophysiological mechanisms elevating stroke risks in cancer patients
• Identification and evaluation of clinical predictors for stroke in oncological settings
• Both pharmacological and non-pharmacological strategies for stroke prevention and patient management in cancer sufferers
• Detailed prognosis factors and clinical predictors of cancer-associated stroke

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Frontiers in Stroke

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