Plant secondary metabolism is a critical area of research that delves into the biosynthesis, regulation, and signaling of secondary metabolites in plants. These natural chemicals are essential for plant survival, facilitating a wide array of biological interactions and providing protection against pathogens, insect herbivory, and environmental stress. Despite their importance, there remain significant gaps in our understanding of the complex biosynthetic pathways, regulatory mechanisms, and signaling processes involved. Recent studies have highlighted the roles of secondary metabolites in modulating nuclear gene expression, plastid biogenesis, cellular homeostasis, and intercellular communication, as well as their contributions to plant growth, development, and reproduction. However, a comprehensive understanding of these processes requires the integration of classical molecular and physiological approaches with advanced omics technologies. This integration is crucial for addressing the existing gaps and advancing our knowledge in this field.

This Research Topic aims to explore the biosynthesis, regulation, and signaling mechanisms of plant secondary metabolites, with a particular focus on their roles in mediating biotic and abiotic stress acclimation. The main objectives include elucidating the biosynthetic pathways, understanding the molecular regulation and transport mechanisms, and investigating the bioactive signals involved in the production of these metabolites. Additionally, the research will examine the regulatory mechanisms and synthetic engineering approaches employed to enhance biosynthesis or modify the structure of secondary metabolites. By addressing these questions, the research aims to provide comprehensive insights into the multifaceted roles of plant secondary metabolites.

To gather further insights into the biosynthesis, regulation, and signaling of plant secondary metabolites, we welcome articles addressing, but not limited to, the following themes:

- The biosynthetic pathways of plant secondary metabolites
- The molecular regulation, transport, and bioactive signals involved in their production
- The regulatory mechanisms and synthetic engineering approaches employed to enhance their biosynthesis or modify their structure
- The functions of secondary metabolites in plant growth, development, and reproduction
- The evolutionary dynamics and adaptation of plant secondary metabolism
- The nutritional, medicinal, and industrial applications of these metabolites as agrochemicals, food additives, and cosmetics

By exploring these themes, we aim to advance our understanding of plant secondary metabolism and its applications in various industries.

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Frontiers in Plant Physiology

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