Stress erythropoiesis is a critical area within hematology that focuses on the body's response to increased demand for red blood cell production, often triggered by conditions such as anemia, hypoxia, or blood loss. Despite significant advancements in understanding the molecular and cellular mechanisms governing erythropoiesis, there remain substantial gaps in knowledge, particularly concerning the regulation and adaptation processes during stress conditions. Recent studies have highlighted the role of specific signaling pathways and transcription factors in modulating erythropoietic responses, yet the complexity of these interactions and their implications for therapeutic interventions are not fully understood. Current debates revolve around the precise mechanisms by which stress erythropoiesis is initiated and sustained, and how these processes can be manipulated to treat hematological disorders. There is a pressing need for more comprehensive investigations to unravel these mechanisms and translate findings into clinical applications.

This research topic aims to deepen the understanding of stress erythropoiesis by exploring the underlying biological processes and identifying potential therapeutic targets. The objective is to address key questions such as: What are the primary signaling pathways involved in stress erythropoiesis? How do these pathways interact with other cellular processes? What are the potential implications for treating anemia and other related disorders? By testing these hypotheses, the research seeks to bridge existing knowledge gaps and contribute to the development of innovative treatment strategies.

To gather further insights in the field of stress erythropoiesis, we welcome articles addressing, but not limited to, the following themes:
- Molecular mechanisms and signaling pathways in stress erythropoiesis
- Role of transcription factors and gene regulation during stress conditions
- Interactions between erythropoiesis and other physiological systems
- Clinical implications and therapeutic strategies for anemia and related disorders
- Advances in diagnostic tools and biomarkers for stress erythropoiesis
- Comparative studies of stress erythropoiesis across different species.

Impact

Frontiers in Hematology

Red Cells, Iron and Erythropoiesis