About this Research Topic
Osteoporosis is a progressive systemic skeletal disease characterized by bone loss, microstructural damage, decreased bone mass, and an increased risk of fracture. This condition primarily results from weakened bone formation and increased bone resorption due to various factors. With the global population aging, the incidence of osteoporosis is on the rise. It is recognized as a critical public health issue, particularly affecting the health of middle-aged and elderly individuals due to its insidious symptoms and the high risk of fractures it entails.
Globally, an osteoporotic fracture occurs approximately every three seconds, encompassing vertebral fractures, hip fractures, distal forearm fractures, and more. Particularly concerning is the one-year mortality rate of individuals who experience hip fractures, reaching 20% due to various complications. Furthermore, about 50% of survivors face disability, rendering them unable to care for themselves and significantly diminishing their quality of life. This results in a substantial increase in the social and economic burden.
Despite these challenges, osteoporosis remains inadequately recognized, and current drug and surgical treatments have limitations. Consequently, addressing osteoporosis and osteoporotic fractures presents an ongoing challenge. Therefore, this Research Topic invites researchers to delve into the latest advancements in understanding the pathogenesis and treatment of osteoporosis and osteoporotic fractures, with the aim of overcoming current obstacles.
We welcome submissions on a wide range of topics, including but not limited to:
- Research on the pathogenesis of osteoporosis, including clinical studies, basic research, and biomechanical investigations.
- Advances in the treatment of osteoporotic fractures, encompassing drug therapy, surgical interventions, and applications of polymer materials.
Globally, an osteoporotic fracture occurs approximately every three seconds, encompassing vertebral fractures, hip fractures, distal forearm fractures, and more. Particularly concerning is the one-year mortality rate of individuals who experience hip fractures, reaching 20% due to various complications. Furthermore, about 50% of survivors face disability, rendering them unable to care for themselves and significantly diminishing their quality of life. This results in a substantial increase in the social and economic burden.
Despite these challenges, osteoporosis remains inadequately recognized, and current drug and surgical treatments have limitations. Consequently, addressing osteoporosis and osteoporotic fractures presents an ongoing challenge. Therefore, this Research Topic invites researchers to delve into the latest advancements in understanding the pathogenesis and treatment of osteoporosis and osteoporotic fractures, with the aim of overcoming current obstacles.
We welcome submissions on a wide range of topics, including but not limited to:
- Research on the pathogenesis of osteoporosis, including clinical studies, basic research, and biomechanical investigations.
- Advances in the treatment of osteoporotic fractures, encompassing drug therapy, surgical interventions, and applications of polymer materials.
Keywords: Osteoporosis, Osteoporotic fracture, Pathogenesis, Treatment
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
