About this Research Topic
The scope of this Research Topic encompasses topics related to neuroinflammation and mood
disorders. We invite original research articles, reviews, and perspectives that address the following themes:
1. Molecular Mechanisms of Neuroinflammation in Mood Disorders: This theme focuses on the cellular and molecular mechanisms through which neuroinflammation contributes to the pathogenesis of mood disorders. Contributions may include studies on the role of microglia, astrocytes, and immune cells in neuroinflammation, as well as the activation of inflammatory signaling pathways in mood disorders.
2. Impact of Neuroinflammation on Mood Regulation: This theme explores the bidirectional relationship between neuroinflammation and mood regulation. It encompasses studies investigating the effects of neuroinflammation on neurotransmitter systems, neuroendocrine pathways, and neural circuits involved in mood regulation.
3. Neuroinflammation and Treatment Response: This theme focuses on the influence of neuroinflammation on the therapeutic response in mood disorders. Contributions may include clinical studies assessing the association between neuroinflammatory markers and treatment outcomes, as well as preclinical studies evaluating the effects of anti-inflammatory interventions on mood-related behaviors.
4. Emerging Therapeutic Strategies: This theme highlights novel therapeutic approaches targeting neuroinflammation in the management of mood disorders. Contributions may include studies on pharmacological agents, neuromodulation techniques, and lifestyle interventions aimed at modulating neuroinflammatory processes and improving mood symptoms.
5. Animal Models in Neuroinflammation and Mood Disorders: Explore the use of animal models to investigate the intricate relationship between neuroinflammation and mood disorders.
6. Translational and Clinical Implications: This theme emphasizes the translational and clinical implications of the neuroinflammation-mood disorders relationship. Contributions may include studies discussing the potential of biomarkers of neuroinflammation for diagnostic and prognostic purposes, as well as the development of personalized treatment strategies based on neuroinflammatory profiles.
We encourage researchers from diverse disciplines, including neuroscience, immunology, psychiatry, and pharmacology, to contribute to this research topic. By bringing together cutting-edge research, this Research Topic aims to advance our understanding of the intricate connections between neuroinflammation and mood disorders, paving the way for innovative therapeutic interventions.
Keywords: Neuroinflammation, Mood Disorders, Inflammatory Signaling, Neurotransmitters, Treatment Response, Therapeutic Strategies, Translational Implications
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.