About this Research Topic
Current research towards the development of therapies for immuno-inflammatory diseases involve several approaches such as small molecules, monoclonal antibodies, nanobodies, therapeutic vaccines, small interfering RNA and stem cell transplantation. Heterocyclic small molecules are small molecules with structures possessing rings incorporating, in addition to carbon atoms, one or more heteroatom such as oxygen, nitrogen, or sulfur. One of the most viable and successful approaches for the development of anti-inflammatory therapeutics has been the introduction of heterocyclic small molecules (either natural or synthetic) which modulate molecular targets and signaling pathways involved in the immuno-inflammatory response.
This Research Topic aims to spotlight recent developments of anti-inflammatory heterocyclic small molecules. High-quality research or review articles are welcomed in this Research Topic. This Topic includes, but is not limited to the following themes:
• Synthesis and biological evaluation of heterocyclic small molecule as anti-inflammatory agents.
• Mechanistic studies and characterization of heterocyclic small molecule anti-inflammatory agents.
• Preclinical and/or clinical studies of heterocyclic small molecule anti-inflammatory agents.
• Drug repurposing studies of heterocyclic small molecules supported by experimental data.
• Computational studies of heterocyclic small molecules supported by experimental data.
Keywords: Anti-inflammatory agents, Heterocyclic compounds, Discovery studies, Mechanisms Studies, Preclinical studies, Clinical studies, Computational studies, Repurposing studies
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