About this Research Topic
This Research Topic aims to present current and novel studies involving the identification of betaine receptors, metabolism, function, and activated signaling pathways in human body, thereby revealing the role of betaine in health, especially its regulatory mechanism, and facilitating the development and utilization of betaine-mediated therapies in human disease.
This Research Topic welcomes original research, systematic and meta-analysis reviews, narrative reviews, and case reports covering the metabolism and alteration of betaine in humans, and its impact on metabolic health and disease. Potential subtopics include but are not limited to the following:
1) Absorption, synthesis, and distribution of betaine in the human body;
2) Betaine alteration and metabolism during disease development;
3) Effect of betaine and its derivatives on tissues/organ development before and after birth;
4) Identification of betaine-mediated receptors and signals in humans, especially using multi-omics;
5) Molecular mechanisms by which betaine modulates health and development in vitro & in vivo.
Keywords: betaine, health, disease, metabolism, nutrition
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.