Consolidated bioprocessing is regarded as a promising solution to enhance sustainability across energy, environmental, and natural resource sectors. Bioprocess engineering for biomass valorisation, synthetic microorganisms, and sustainability modelling are the main components of integrated biorefinery system development. Such biomass-to-bioproduct pipelines have the potential to initiate a circular bioeconomy, foster waste reduction practices, and contribute significantly to global decarbonization efforts. However, the commercialization of biorefineries faces challenges due to technology complexity, costly processing, feedstock uncertainty, and biomass-derived inhibitory effects on microbial cultures. To date, the integration of metabolic engineering and biomass deconstruction has emerged as a hot topic. This approach aims to facilitate platform chemical production through the construction of bioprocessing pathways, opening up exciting possibilities for creating a diverse range of valuable products from renewable biomass resources. Therefore, advanced research in synthetic biology, bioproduct innovation, and bioprocessing design for industrial practices is essential for securing the long-term sustainability of integrated biorefineries.

This research topic aims to have impactful perspectives on advanced biorefinery improvement, encompassing biomass valorisation through microbial cultures, metabolic pathway construction for high-value bioproduct synthesis, and intelligent processing design for the development of future biorefinery industries. According to these areas of research, the future outlook on potential economic cost and environmental viability of consolidated bioprocessing can be conceptualized. This Research Topic seeks high-quality research focusing on novel bioprocessing design and technology development for high-value platform chemical and biofuel productions.

To gather further insights into the boundaries of bioprocessing design and technology development, we welcome articles addressing, but not limited to, the following themes:
- Synthetic microorganisms
- Metabolic engineering
- Biocatalysts technology for bioproduct productions
- Bioprocessing design for industrial practices
- Biomass valorisations
- Bioproduct innovations
- Bioprocessing modelling
- Microbial engineering for bioproduct production

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Frontiers in Industrial Microbiology

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