About this Research Topic
Intestinal dysbiosis is associated with diseases that affect the intestines but also have implications throughout the body, including the brain, lungs, heart, joints, skin, and eyes, among others. Understanding the impact of intestinal dysbiosis on various organ systems is crucial for unraveling the complex mechanisms underlying disease development and progression. By investigating the intricate interactions between the gut microbiome and different organs, we can identify potential therapeutic targets and novel interventions for restoring microbial balance and improving health outcomes. This Research Topic aims to explore the wide-ranging implications of intestinal dysbiosis on organs beyond the intestines.
Researchers are encouraged to submit original research articles, reviews, mini-reviews, systematic reviews, case reports, perspectives, short communications, theoretical papers, opinions, and methods focusing on the pathophysiological connections between the intestine and other organs that will cover topics such as (but not limited to):
- brain-gut axis
- lung-intestine axis
- (kidney)-heart-gut axis
- dysbiosis and immune metabolism
- relationship between intestinal microorganisms and mucosal immunity
- influence of the intestine on psychic alterations and psycho-social behavior
- role of the microbiota in immune-mediated and metabolic diseases
- intestinal microbiota and sport
- cancer and intestinal microorganisms
- nutritional modulation of the intestinal microbiota
- prebiotics, probiotics, postbiotics, or fecal transplantation as future therapeutic strategies
Keywords: host-microbiota interaction, immuno-metabolism, inflammation, intestinal dysbiosis, intestinal neuroendocrine activity, pathophysiological axes of the gut
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.