About this Research Topic
However, traditional methods for separating and characterizing EVs have notable limitations, including low separation purity, yields, specificity, repeatability, and high cost. Therefore, the development of rapid and effective methods for detecting and analyzing EVs in body fluids is imperative. Point-of-care testing (POCT), particularly biosensor-based detection, has gained significant attention as a promising technology to improve the sensitivity of EV extraction due to its instant analysis, ease of use, high sensitivity, rapid response, specificity, and low sample requirement. The advancement of biosensors has enabled their application in clinical translations. Additionally, EVs loaded with therapeutic molecules, such as miRNAs, face challenges of low efficacy and limited targeting. To address these issues, tailored therapeutic EVs designed through engineering approaches have gained focus in recent years.
This Research Topic focuses on emerging technologies in EVs field for biomedical applications and challenges involved in their clinic translations. The topic welcomes, but is not limited to, Original Research, Reviews, and Prospective in the following research areas:
• Advanced nanosystems for EV detection
• Advanced approaches to EV engineering strategies
• EV cargo loading for disease therapy
• Advanced biomaterial based on EV
• New strategies for improving EV isolation and purification
Keywords: extracellular vesicles, theranostics, biosensor, nanotechnology
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.