About this Research Topic
The intricate interplay of bones, cartilage, muscles, tendons, ligaments and brain signaling within the locomotor apparatus forms the foundation of human movement. In the pursuit of optimizing the rehabilitation and treatment of musculoskeletal injuries and disorders, scientists and clinicians are delving into the realm of tissue repair modelling. This innovative field combines the principles of tissue regeneration with cutting-edge medical research to better understand and predict the complex processes involved in healing and restoring function in the locomotor apparatus.
Injuries and degenerative conditions within the locomotor apparatus are common, and effective treatment and rehabilitation are crucial for maintaining an individual's quality of life. This research topic, which includes in vitro, ex vivo and in vivo models of the locomotor apparatus, is not only a promising avenue for enhancing patient outcomes but also a fascinating area of scientific inquiry. By harnessing the power of biological models and state-of-the-art techniques, researchers aim to elucidate the dynamic mechanisms that govern tissue regeneration and functional recovery in the locomotor system.
The problem of tissue repair in the locomotor apparatus is rooted in the complexity of understanding and predicting the intricate processes involved in the healing and regeneration of tissues, including bones, cartilage, muscles, tendons, ligaments and brain. The current challenge lies in comprehending the genetic, cellular, and biomechanical mechanisms governing tissue repair and leveraging this knowledge to develop more effective treatment strategies.
This multidisciplinary approach opens up new horizons for personalized medicine, as clinicians can tailor treatment strategies to the unique characteristics of each patient's injury and response to therapy. Whether it's a professional athlete recovering from a sports-related injury, an aging individual grappling with degenerative conditions, or a child with a congenital musculoskeletal disorder, models of tissue repair offer hope for more effective treatments and improved quality of life.
Join us as we explore the exciting advancements in current and new models of tissue repair within the locomotor apparatus. Our journey will take us through the integration of biological and biomechanical principles with computational technology, the development of patient-specific treatment plans, and the potential to revolutionize the way we address musculoskeletal injuries and disorders. Together, we will venture into the future of medicine and rehabilitation, where the locomotor apparatus is better understood, more effectively treated, and where the boundaries of human movement are pushed ever further.
In this Research Topic we welcome Original Research Papers, Perspectives, Reviews and Mini Reviews, Opinion, and Editorial Commentary on in vitro, ex vivo and in vivo models of tissue repair within the locomotor apparatus from human, animal and marine origin.
Articles may involve one or more of the following topics:
• Bone and/or cartilage repair models;
• Muscle regeneration models;
• Neuro-muscular circuitry
• Tendon and ligament repair models;
• Genomic and transcriptomic modeling;
• Patient-specific tissue repair models
• Biomaterials and scaffold modeling;
• Gene therapy.
A full list of accepted article types, including descriptions, can be found at this link.
Injuries and degenerative conditions within the locomotor apparatus are common, and effective treatment and rehabilitation are crucial for maintaining an individual's quality of life. This research topic, which includes in vitro, ex vivo and in vivo models of the locomotor apparatus, is not only a promising avenue for enhancing patient outcomes but also a fascinating area of scientific inquiry. By harnessing the power of biological models and state-of-the-art techniques, researchers aim to elucidate the dynamic mechanisms that govern tissue regeneration and functional recovery in the locomotor system.
The problem of tissue repair in the locomotor apparatus is rooted in the complexity of understanding and predicting the intricate processes involved in the healing and regeneration of tissues, including bones, cartilage, muscles, tendons, ligaments and brain. The current challenge lies in comprehending the genetic, cellular, and biomechanical mechanisms governing tissue repair and leveraging this knowledge to develop more effective treatment strategies.
This multidisciplinary approach opens up new horizons for personalized medicine, as clinicians can tailor treatment strategies to the unique characteristics of each patient's injury and response to therapy. Whether it's a professional athlete recovering from a sports-related injury, an aging individual grappling with degenerative conditions, or a child with a congenital musculoskeletal disorder, models of tissue repair offer hope for more effective treatments and improved quality of life.
Join us as we explore the exciting advancements in current and new models of tissue repair within the locomotor apparatus. Our journey will take us through the integration of biological and biomechanical principles with computational technology, the development of patient-specific treatment plans, and the potential to revolutionize the way we address musculoskeletal injuries and disorders. Together, we will venture into the future of medicine and rehabilitation, where the locomotor apparatus is better understood, more effectively treated, and where the boundaries of human movement are pushed ever further.
In this Research Topic we welcome Original Research Papers, Perspectives, Reviews and Mini Reviews, Opinion, and Editorial Commentary on in vitro, ex vivo and in vivo models of tissue repair within the locomotor apparatus from human, animal and marine origin.
Articles may involve one or more of the following topics:
• Bone and/or cartilage repair models;
• Muscle regeneration models;
• Neuro-muscular circuitry
• Tendon and ligament repair models;
• Genomic and transcriptomic modeling;
• Patient-specific tissue repair models
• Biomaterials and scaffold modeling;
• Gene therapy.
A full list of accepted article types, including descriptions, can be found at this link.
Keywords: Muscle Regeneration Models, Cartilage Repair Models, Bone Repair Models, Tendon and Ligament Repair Models, Genomic and Transcriptomic Modeling, Patient-Specific Tissue Repair Models, Biomaterials and Scaffold Modeling, Gene Therapy
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