About this Research Topic
The current state of research in the brain glioma immune microenvironment centers on investigating the underlying mechanisms that govern the crosstalk between tumor cells and immune components. By exploring the latest therapeutic strategies targeting the glioma immune landscape, we can potentially revolutionize glioma treatment and overcome immunotherapy resistance. This Research Topic aims to catalyze continued research, innovation, and collaboration among scientists, clinicians, and industry stakeholders. By unraveling and collecting insights into the mechanisms shaping the glioma immune landscape, understanding immunotherapy resistance, and advancing relevant translational research, we can pave the way toward more effective and personalized therapeutic interventions. This progress brings us one step closer to defeating the formidable challenge of brain gliomas and improving the lives of affected patients worldwide.
We welcome submissions of original research, cutting-edge reviews, clinical, pathological, and translational studies related to, but not limited to, the following areas:
(1) Mechanisms of crosstalk between glioma cells and the immune microenvironment, both in basic and clinical settings.
(2) Novel neoadjuvant treatment strategies for glioma immunotherapy, aiming to improve patient outcomes.
(3) Technical advancements in the detection of immunotherapy targets specific to glioma.
(4) New biomarkers that can guide and monitor the effectiveness of immunotherapy treatment in glioma patients.
(5) Pathological and molecular features of gliomas following immunotherapy to understand treatment responses and potential adverse effects.
(6) Prediction models for evaluating the pathologic response in glioma patients undergoing immunotherapy.
Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.
Keywords: glioma, immune microenvironment, immunotherapy, pathological features, molecular features
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.