About this Research Topic
The field of immunology has recently seen a surge of interest in the roles of circular RNAs (circRNAs) and microRNAs (miRNAs) in immune-related diseases. These non-coding RNAs are increasingly recognized for their involvement in regulating immune responses and their potential as biomarkers for diagnosis, therapeutic effects, and prognosis in various immunological disorders. Despite the promising findings, the exact mechanisms by which circRNAs and miRNAs influence immune cell differentiation, disease response, and the balance between pathogens and immune cells remain largely unexplored. Recent studies have begun to uncover the multifaceted functions of circRNAs in the immune system, yet significant gaps persist in understanding their regulatory roles and interactions with miRNAs. Addressing these gaps is crucial, as it could lead to novel therapeutic strategies for treating rare and challenging immune-related diseases.
This research topic aims to illuminate the emerging role of circRNAs and microRNAs in immune-related diseases. It seeks to enhance understanding of their biogenesis, action mechanisms, and clinical utility, particularly in the context of immunological disorders. The research will explore how these non-coding RNAs can serve as potential therapeutic targets and biomarkers, and will investigate their interaction networks using systems biology-based approaches. By doing so, the research aims to provide insights into the gene expression dynamics that underpin the development and progression of immune diseases.
To gather further insights into the complex interactions of circRNAs and microRNAs in immune-related diseases, we welcome articles addressing, but not limited to, the following themes:
- Investigating the role of circRNAs and microRNAs in immune-related diseases.
- Highlighting the possible role of circRNAs and miRNAs as regulators in immune diseases based on regulatory networks.
- Exploring the biogenesis and action mechanisms of circRNAs and microRNAs in immune responses.
- Evaluating the potential of circRNAs and microRNAs as biomarkers for diagnosis and prognosis in immunological disorders.
- Systems biology approaches to map circRNAs and microRNAs interaction networks in immune diseases.
This research topic aims to illuminate the emerging role of circRNAs and microRNAs in immune-related diseases. It seeks to enhance understanding of their biogenesis, action mechanisms, and clinical utility, particularly in the context of immunological disorders. The research will explore how these non-coding RNAs can serve as potential therapeutic targets and biomarkers, and will investigate their interaction networks using systems biology-based approaches. By doing so, the research aims to provide insights into the gene expression dynamics that underpin the development and progression of immune diseases.
To gather further insights into the complex interactions of circRNAs and microRNAs in immune-related diseases, we welcome articles addressing, but not limited to, the following themes:
- Investigating the role of circRNAs and microRNAs in immune-related diseases.
- Highlighting the possible role of circRNAs and miRNAs as regulators in immune diseases based on regulatory networks.
- Exploring the biogenesis and action mechanisms of circRNAs and microRNAs in immune responses.
- Evaluating the potential of circRNAs and microRNAs as biomarkers for diagnosis and prognosis in immunological disorders.
- Systems biology approaches to map circRNAs and microRNAs interaction networks in immune diseases.
Keywords: circRNAs, miRNA, Immune diseases, Regulatory network, System Biology
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
