There is a close connection between the eye and the brain. The retina and the optic nerve are important components of the central nervous system (CNS). Moreover, about 50% of our brain is involved in visual processing. Thus, diseases of the CNS may lead to vision issues. Neuro-ophthalmology is a subspecialty that merges the fields of neurology and ophthalmology. Neuro-ophthalmologists often focus on neurological and systemic diseases that have manifestations in the visual system.

Due to the special optical properties of the eye, the retina and optic nerve head have become the only parts of the CNS that can be directly observed in vitro. This means that imaging examinations play an important role in neuro-ophthalmologic diseases. Multimodal imaging is often necessary for neuro-ophthalmologists to obtain a complete clinical picture of patients with neuro-ophthalmologic diseases. With the advancement of multimodal imaging techniques, novel insights into neuro-ophthalmologic diseases can be expected.

This Research Topic mainly focuses on advances in the preclinical/clinical applications and the new prospects of multimodal imaging in neuro-ophthalmic diseases (e.g. optic neuritis, hereditary optic neuropathy, optic nerve tumors, etc). Papers in this Research Topic may inspire readers with a deeper interpretation of these neuro-ophthalmic diseases.

We welcome submissions on preclinical and clinical studies of original research articles, methods, reviews, mini-reviews, perspectives, clinical trials, case reports, and brief research reports. Submissions related to any aspect of Neuro-ophthalmology imaging are expected.

We encourage authors to focus on:

1) disorders where new imaging techniques can improve the understanding or influence the clinical management (such as Multicolor Imaging and Adaptive Optics Imaging)；
or
2) new discoveries of diseases using classical imaging techniques (For example, an author found that a certain indicator of OCT can predict the risk of recurrence in patients with optic neuritis).

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Frontiers in Neurology

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