About this Research Topic
Carbon dioxide (CO2) is an important carbon feedstock and its valorization is one of the most important steps towards a carbon neutral bio-economy. While most commodity chemicals are derived exclusively from fresh fossil resources like oil, gas and coal, fermentative biomanufacturing enables sustainable, targeted production of desired chemicals from C1 carbon sources like CO2.
Recently, a variety of synthetic CO2-fixing cycles and autotrophic microorganisms (natural and artificial) have been described. However, the direct use of CO2 in biotechnology still faces several challenges and limitations. Nevertheless, recent examples show that promising alternative routes can be developed. Current efforts in this area combine chassis strain development with process engineering to advance successful CO2-based biotechnological processes. To achieve this, the development of genetic tools for strain manipulation, the integration of hydrogen-driven biotransformations, new reactor concepts for (gas) fermentation to achieve high cell densities, and a better understanding of cell physiology during (gas) fermentation are being explored.
To highlight recent efforts in the field, the proposed Research Topic aims to present the latest scientific advances in the biological conversion of CO2, including the genetic engineering of autotrophic microorganisms, hydrogen-driven biotransformations, and the development of efficient (gas) fermentation concepts to increase competitiveness and pave the way for efficient future CO2-based biotechnological processes.
We encourage the submission of original research articles, perspectives and reviews, with topics of interest including but not limited to:
the development of synthetic metabolic pathways towards CO2 utilization
the engineering of CO2 utilizing enzymes for integration in (artificial) metabolic routes
the development of novel genetic tools for strain engineering of autotrophic microorganisms
the integration of autotrophic CO2 fixation with hydrogen-driven biotransformations
the integration of strain and process engineering for the efficient production of chemicals from CO2
the development of novel reactor concepts for (gas) fermentations
Recently, a variety of synthetic CO2-fixing cycles and autotrophic microorganisms (natural and artificial) have been described. However, the direct use of CO2 in biotechnology still faces several challenges and limitations. Nevertheless, recent examples show that promising alternative routes can be developed. Current efforts in this area combine chassis strain development with process engineering to advance successful CO2-based biotechnological processes. To achieve this, the development of genetic tools for strain manipulation, the integration of hydrogen-driven biotransformations, new reactor concepts for (gas) fermentation to achieve high cell densities, and a better understanding of cell physiology during (gas) fermentation are being explored.
To highlight recent efforts in the field, the proposed Research Topic aims to present the latest scientific advances in the biological conversion of CO2, including the genetic engineering of autotrophic microorganisms, hydrogen-driven biotransformations, and the development of efficient (gas) fermentation concepts to increase competitiveness and pave the way for efficient future CO2-based biotechnological processes.
We encourage the submission of original research articles, perspectives and reviews, with topics of interest including but not limited to:
the development of synthetic metabolic pathways towards CO2 utilization
the engineering of CO2 utilizing enzymes for integration in (artificial) metabolic routes
the development of novel genetic tools for strain engineering of autotrophic microorganisms
the integration of autotrophic CO2 fixation with hydrogen-driven biotransformations
the integration of strain and process engineering for the efficient production of chemicals from CO2
the development of novel reactor concepts for (gas) fermentations
Keywords: Biotechnology, Carbon Dioxide, Hydrogen, Enzymes, Microbial Fermentation, Gas fermentation, Autotrophy
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
