About this Research Topic
The health of human beings depends on the integrity of the mechanical barrier function of several organs like skin, lungs, and intestine which interact with either exotoxin or endotoxin to prevent them from evading. Besides the mechanical barrier function, immunity is another important barrier function, exerting a protective effect synergistically with the mechanical barrier function. However, both immune deficiency and overactivation of the immune response will result in pathological conditions. Many traditional medicines have been proven to prevent or cure disease by restoring the barrier function of the human body, either through reconstructing a balanced immune system or restoring the mechanical barrier of skin, lungs, and intestine. Therefore, exploring the potential function and mechanism for traditional medicine restoring the barrier function of the skin, lungs, and intestine will help exploit traditional medicine with more scientific evidence.
The problem that you would like to address in this Research Topic is to reveal the specific effect of traditional medicine (Traditional Chinese medicine, Kampo, African, or other traditional medicine) on the barrier function (mechanical and/or immune-related one) of the intestine, lung, and skin, especially for those that have traditional applications in the treatment of diseases of intestine, lung, and skin, and to clarify the underlying mechanism, especially immunity-related ones. To achieve these objectives, ex vivo or in vivo experiments are required to assure the credibility of the experimental results, and research that reports only the in vitro results will not be considered for this Research Topic. Additionally, the paper review the recent advances in traditional medicine restoring the barrier function of the intestine, lung, and skin, and their corresponding mechanisms are also welcomed. Papers reporting post-transcriptional or post-translational mechanisms are encouraged and will give certain priority due to the novelty of these two types of cell signaling modulation patterns. The chemical constituents of the traditional medicine used for the pharmacological study are supposed to be clear (either reported by the literature or clarified by chemical studies).
Researcher papers regarding traditional medicine modulating either mechanical barrier function or immunologic barrier function are welcomed, including but not limited to:
-Effects and mechanism study on intestinal barrier function
-Effects and mechanism study on intestinal flora and Immunity
-Effects and mechanism study on normal lung cells (studies on lung tumor cells are not acceptable)
-Effects and mechanism study on lung immunity
-Effects and mechanism study on the mechanic barrier function of the skin
-Effects and mechanism study on skin immunity
-Review papers that summarize the above research contents
All the manuscripts submitted to this project will be peer-reviewed and need to fully comply with the Four Pillars of Best Practice in Ethnopharmacology (you can freely download the full version here). Importantly, please ascertain that the ethnopharmacological context is clearly described (pillar 3d) and that the material investigated is characterised in detail (pillars 2 a and b ).
The problem that you would like to address in this Research Topic is to reveal the specific effect of traditional medicine (Traditional Chinese medicine, Kampo, African, or other traditional medicine) on the barrier function (mechanical and/or immune-related one) of the intestine, lung, and skin, especially for those that have traditional applications in the treatment of diseases of intestine, lung, and skin, and to clarify the underlying mechanism, especially immunity-related ones. To achieve these objectives, ex vivo or in vivo experiments are required to assure the credibility of the experimental results, and research that reports only the in vitro results will not be considered for this Research Topic. Additionally, the paper review the recent advances in traditional medicine restoring the barrier function of the intestine, lung, and skin, and their corresponding mechanisms are also welcomed. Papers reporting post-transcriptional or post-translational mechanisms are encouraged and will give certain priority due to the novelty of these two types of cell signaling modulation patterns. The chemical constituents of the traditional medicine used for the pharmacological study are supposed to be clear (either reported by the literature or clarified by chemical studies).
Researcher papers regarding traditional medicine modulating either mechanical barrier function or immunologic barrier function are welcomed, including but not limited to:
-Effects and mechanism study on intestinal barrier function
-Effects and mechanism study on intestinal flora and Immunity
-Effects and mechanism study on normal lung cells (studies on lung tumor cells are not acceptable)
-Effects and mechanism study on lung immunity
-Effects and mechanism study on the mechanic barrier function of the skin
-Effects and mechanism study on skin immunity
-Review papers that summarize the above research contents
All the manuscripts submitted to this project will be peer-reviewed and need to fully comply with the Four Pillars of Best Practice in Ethnopharmacology (you can freely download the full version here). Importantly, please ascertain that the ethnopharmacological context is clearly described (pillar 3d) and that the material investigated is characterised in detail (pillars 2 a and b ).
Keywords: Traditional medicines, barrier function, immunity, intestine, lung, skin
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
