About this Research Topic
Gut microbiota and oral microbiota play crucial roles in human health. Emerging evidence has demonstrated that they both have vital functions, including training the immune system, protecting against pathogens, and collaborating with host cells to metabolize food and nutrients. Imbalances or alterations in the gut microbiota, known as dysbiosis, have been linked to various conditions such as inflammatory bowel diseases, obesity, diabetes, cancers, and mental health disorders. Similarly, an imbalance in the oral microbiota can lead to the development of dental caries (cavities), periodontal diseases (gum diseases), and oral infections. Certain oral bacterial pathogens, including Fusobacterium, Campylobacter, Prevotella, Pseudomonas, and Capnocytophaga, are associated with lung, oral, esophageal, stomach, pancreatic, and colorectal cancers.
It is intriguing to note that the gut microbiota and oral microbiota are not isolated systems but interconnected. They share common microbial species, and the oral microbiota can act as a reservoir for certain bacteria that can translocate to the gut. Conversely, the gut microbiota can influence the composition and diversity of the oral microbiota through immune responses and systemic factors. Moreover, the gut and oral microbiota are interconnected with other microbiota systems, contributing to maintaining a healthy state and preventing diseases such as obesity and autoimmune disorders.
Understanding the intricate relationship between gut microbiota and oral microbiota is the purpose of this Research Topic and it is crucial for advancing our knowledge of human health and developing potential therapeutic interventions.
It is intriguing to note that the gut microbiota and oral microbiota are not isolated systems but interconnected. They share common microbial species, and the oral microbiota can act as a reservoir for certain bacteria that can translocate to the gut. Conversely, the gut microbiota can influence the composition and diversity of the oral microbiota through immune responses and systemic factors. Moreover, the gut and oral microbiota are interconnected with other microbiota systems, contributing to maintaining a healthy state and preventing diseases such as obesity and autoimmune disorders.
Understanding the intricate relationship between gut microbiota and oral microbiota is the purpose of this Research Topic and it is crucial for advancing our knowledge of human health and developing potential therapeutic interventions.
Keywords: Gut microbiota, oral microbiota, immune system, oral infections, gut microbiota/oral microbiota relationship
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