Discovered one century ago, bacteriophages were immediately employed as antibacterials due to their lytic property. Today it has become clear that bacteriophages are involved not only in shaping bacteria communities and also in regulating the human immune response. The synergy between bacteria and immune modulation underlies many aspects of human health, including cancer development. In particular, bacteriophages and the immune system work in concert to fight bacterial infections.
The Goal of this Research Topic is to provide an update on the current knowledge regarding the role of bacteriophages in modulating the immune response.
This Research Topic is focused on the interrelation between bacteriophages and the immune system. The topic will include articles regarding how bacteriophages help the correct development of the immune system in newborns, as well as modulating the immune response in adults, in particular by reducing the level of inflammation. The synergism between bacteriophages and the immune system in contrasting bacterial infections will also be an essential feature to be described, given its therapeutic implications. The final focus of the proposed topic will be the relationship between an imbalance in the combination of bacteriophage-immunity and the development of diseases, providing a link with applied medicine. Either experimental articles or reviews of the publications will cover these features.
Keywords:
bacteriophage, immunity, virology, inflammation, immunomodulation, phage-immune synergy
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Discovered one century ago, bacteriophages were immediately employed as antibacterials due to their lytic property. Today it has become clear that bacteriophages are involved not only in shaping bacteria communities and also in regulating the human immune response. The synergy between bacteria and immune modulation underlies many aspects of human health, including cancer development. In particular, bacteriophages and the immune system work in concert to fight bacterial infections.
The Goal of this Research Topic is to provide an update on the current knowledge regarding the role of bacteriophages in modulating the immune response.
This Research Topic is focused on the interrelation between bacteriophages and the immune system. The topic will include articles regarding how bacteriophages help the correct development of the immune system in newborns, as well as modulating the immune response in adults, in particular by reducing the level of inflammation. The synergism between bacteriophages and the immune system in contrasting bacterial infections will also be an essential feature to be described, given its therapeutic implications. The final focus of the proposed topic will be the relationship between an imbalance in the combination of bacteriophage-immunity and the development of diseases, providing a link with applied medicine. Either experimental articles or reviews of the publications will cover these features.
Keywords:
bacteriophage, immunity, virology, inflammation, immunomodulation, phage-immune synergy
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.