Metals areas are critical components of more than 30% of all proteins and affect both structure and function of proteins, but also affect the structure and function of other all biomolecules including nucleic acids, carbohydrates and lipids. The critical chemistry for the function of biomolecules and their structure or any biomedical and therapeutic applications which include spectroscopic or diagnostic information detailing information on any biological or biometal problem which often involves redox chemistry or hydrolytic chemistry facilitating catalysis and energy conversions. This issue will cover manuscripts describing all areas of chemical biology which will focus on problems that are investigated using molecular chemistry, chemical methods or approaches including applications of chemistry, or any type of function/catalysis related to application of metal ions whether that be therapeutical or functional and reflect their natural function.

The 16th International Symposium on Applied Bioinorganic Chemistry, held in the University of Ioannina in Greece, covers the specific areas of Metals in Medicine and covered biological and medical applications, method development and biomimetic materials.

This Research Topic aims to collate papers based on the presentations at the ISABC-16, surround the field of Bioinorganic Chemistry, and Medicine employing metal ions in the context of Chemical biology. We are interested in all phenomena, problems, and topics in which metal ions plays a role in the structure, function or applications in biology or medicine. We are particularly interested in original research papers which will detail the chemistry involved. We do welcome contributions from scientist interested in this general area, but that was not able to attend the conference.

In this Research Topic we invite submissions addressing the biological and biomedical effects of, but not limited to, the following metals:
• Transition metals
• Main group metal
• Lanthanides
• Actinides

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Frontiers in Chemical Biology

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