About this Research Topic
The goal is to showcase sex and gender difference research by tumor site including in sites where one or the other sex is over or underrepresented and connect this to growing data and the placement of data analysis tool that will identify and harness sex differences with transferability to other aspects to medicine.
Each topic will be organised by cancer tumor sites as typically approached in guidelines and oncology departments to include the larger oncologic sites (central nervous system, head and neck, genitourinary, gastrointestinal, lung, hematology oncology) as well as sites that are sex specific (prostate, testicula, ovarian cancer) or have significant discrepancy in sex distribution (eg. breast cancer). Sex differences will be connected to biological triggers at each hierarchical level ( genomic, transcriptomic, proteomic) and to data in terms of data location (in both geographical as well storage sense), pockets of data growth and analysis and finally areas where sex difference data has crossed the boundaries from bench to bedside and/or is employed to alter management in the clinic.
Keywords: malignancy, biomarkers, response, prognosis, personalised medicine
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