The central nervous system has a limited regeneration ability; following injury, signaling pathways and protein expression triggers apoptosis and prevents cell differentiation. Therefore, there is increasing interest in regenerative neurogenesis and methods to enhance repair following injury. The field of regenerative neurogenesis has rapidly grown during the last decades. These advances have been fostered by improvements in the research techniques that enable us to gather insights from different approaches. Despite recent advances, multiple aspects still need to be addressed for a complete understanding of regenerative neurogenesis.
In this Research Topic, Frontiers in Neuroscience is looking to address key aspects of regenerative neurogenesis in order to promote the discussion around this topic and to facilitate knowledge dissemination. We will explore the intrinsic mechanisms that promote and prevent regeneration following nervous system injury. The Topic aims to highlight the recent advances in interventions aiming to enhance regeneration, including cell transplants and bionic nerve scaffolds. We also welcome contributions that look into the future and define the directions that the field will take in the coming years; What have been the key discoveries so far? What are the most pressing matters that need to be addressed? Where is regenerative neurogenesis going to take us in the coming years?
We particularly welcome submission of Original Research, Review, Methods, Hypothesis & Theory, and Perspective articles on the following sub-topics:
• Identifying regeneration mechanisms in regenerating species and exploring the current mechanisms implicated
following CNS injury in non-regenerating species
• Investigating evolutionary constraints on mammalian CNS regeneration
• Identifying the differences between animal models and human/primate brains to devise potential solutions to
address the disparity between preclinical and clinical studies
• Creating novel techniques for enhancing regenerative neurogenesis and gliosis
• Understanding the genetic underpinnings of regenerative neurogenesis
Keywords:
regeneration, regenerative neurogenesis
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
The central nervous system has a limited regeneration ability; following injury, signaling pathways and protein expression triggers apoptosis and prevents cell differentiation. Therefore, there is increasing interest in regenerative neurogenesis and methods to enhance repair following injury. The field of regenerative neurogenesis has rapidly grown during the last decades. These advances have been fostered by improvements in the research techniques that enable us to gather insights from different approaches. Despite recent advances, multiple aspects still need to be addressed for a complete understanding of regenerative neurogenesis.
In this Research Topic, Frontiers in Neuroscience is looking to address key aspects of regenerative neurogenesis in order to promote the discussion around this topic and to facilitate knowledge dissemination. We will explore the intrinsic mechanisms that promote and prevent regeneration following nervous system injury. The Topic aims to highlight the recent advances in interventions aiming to enhance regeneration, including cell transplants and bionic nerve scaffolds. We also welcome contributions that look into the future and define the directions that the field will take in the coming years; What have been the key discoveries so far? What are the most pressing matters that need to be addressed? Where is regenerative neurogenesis going to take us in the coming years?
We particularly welcome submission of Original Research, Review, Methods, Hypothesis & Theory, and Perspective articles on the following sub-topics:
• Identifying regeneration mechanisms in regenerating species and exploring the current mechanisms implicated
following CNS injury in non-regenerating species
• Investigating evolutionary constraints on mammalian CNS regeneration
• Identifying the differences between animal models and human/primate brains to devise potential solutions to
address the disparity between preclinical and clinical studies
• Creating novel techniques for enhancing regenerative neurogenesis and gliosis
• Understanding the genetic underpinnings of regenerative neurogenesis
Keywords:
regeneration, regenerative neurogenesis
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.