EDITORIAL
Published on 08 Jun 2018
Editorial: Safety Pharmacology – Risk Assessment QT Interval Prolongation and Beyond
doi 10.3389/fphys.2018.00678
- 3,251 views
- 11 citations
- Frontiers in Physiology
- Integrative Physiology
- Research Topics
- Safety Pharmacology - Risk Assessment QT Interval Prolongation and Beyond
Safety Pharmacology - Risk Assessment QT Interval Prolongation and Beyond
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Articles
ORIGINAL RESEARCH
Published on 20 Apr 2018
Proton Pump Inhibitors and Serum Magnesium Levels in Patients With Torsades de Pointes
doi 10.3389/fphar.2018.00363
- 14,645 views
- 34 citations
ORIGINAL RESEARCH
Published on 12 Apr 2018
Determinants of Isoform-Specific Gating Kinetics of hERG1 Channel: Combined Experimental and Simulation Study
doi 10.3389/fphys.2018.00207
- 5,002 views
- 25 citations
ORIGINAL RESEARCH
Published on 07 Feb 2018
Structural Immaturity of Human iPSC-Derived Cardiomyocytes: In Silico Investigation of Effects on Function and Disease Modeling
doi 10.3389/fphys.2018.00080
- 25,107 views
- 134 citations
ORIGINAL RESEARCH
Published on 01 Feb 2018
Digging into Lipid Membrane Permeation for Cardiac Ion Channel Blocker d-Sotalol with All-Atom Simulations
doi 10.3389/fphar.2018.00026
- 4,849 views
- 24 citations
ORIGINAL RESEARCH
Published on 19 Jan 2018
A Hybrid Model for Safety Pharmacology on an Automated Patch Clamp Platform: Using Dynamic Clamp to Join iPSC-Derived Cardiomyocytes and Simulations of Ik1 Ion Channels in Real-Time
doi 10.3389/fphys.2017.01094
- 5,079 views
- 49 citations
ORIGINAL RESEARCH
Published on 05 Jan 2018
Action Potential Recording and Pro-arrhythmia Risk Analysis in Human Ventricular Trabeculae
doi 10.3389/fphys.2017.01109
- 6,654 views
- 22 citations
MINI REVIEW
Published on 04 Jan 2018
Applications of Dynamic Clamp to Cardiac Arrhythmia Research: Role in Drug Target Discovery and Safety Pharmacology Testing
doi 10.3389/fphys.2017.01099
- 4,005 views
- 23 citations
ORIGINAL RESEARCH
Published on 04 Jan 2018
Composite Biomarkers Derived from Micro-Electrode Array Measurements and Computer Simulations Improve the Classification of Drug-Induced Channel Block
doi 10.3389/fphys.2017.01096
- 2,229 views
- 11 citations
ORIGINAL RESEARCH
Published on 19 Dec 2017
Global Optimization of Ventricular Myocyte Model to Multi-Variable Objective Improves Predictions of Drug-Induced Torsades de Pointes
doi 10.3389/fphys.2017.01059
- 3,730 views
- 35 citations
ORIGINAL RESEARCH
Published on 19 Dec 2017
Adult Human Primary Cardiomyocyte-Based Model for the Simultaneous Prediction of Drug-Induced Inotropic and Pro-arrhythmia Risk
doi 10.3389/fphys.2017.01073
- 7,601 views
- 58 citations
ORIGINAL RESEARCH
Published on 12 Dec 2017
Tailoring Mathematical Models to Stem-Cell Derived Cardiomyocyte Lines Can Improve Predictions of Drug-Induced Changes to Their Electrophysiology
doi 10.3389/fphys.2017.00986
- 6,840 views
- 46 citations
Published in
Frontiers in Physiology
- Integrative Physiology
- Clinical and Translational Physiology
- Systems Biology ArchiveOffline
- Cardiac Electrophysiology
- Computational Physiology and Medicine
- Membrane Physiology and Membrane Biophysics
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- 35kArticle downloads