About this Research Topic
Environmental microbiomes consist of diverse microbial communities that inhabit various natural and built environments, such as soil, water, air, and indoor surfaces. These microbial communities can produce a wide range of metabolites, including small organic molecules, volatile organic compounds (VOCs), and secondary metabolites. These metabolites can have direct or indirect effects on human health by modulating the immune system, triggering inflammatory responses, or promoting the growth of pathogenic microorganisms. Additionally, environmental microbiomes can also influence the composition and function of human-associated microbiomes, such as the respiratory microbiome, which may further contribute to respiratory health or disease.
Respiratory diseases, such as asthma, chronic obstructive pulmonary disease (COPD), and respiratory infections, have significant impacts on public health and healthcare systems worldwide. The incidence and prevalence of these diseases are influenced by a range of environmental factors, including air pollution, allergens, and microbial exposures. However, the precise mechanisms through which environmental microbiomes and their metabolites contribute to respiratory health and disease remain poorly understood.
The scope of this special issue collection encompasses, but is not limited to:
1. Investigations of the composition and diversity of environmental microbiomes in relation to respiratory diseases, including indoor and outdoor environments, occupational settings, and geographical variations.
2. Studies on the production, detection, and characterization of microbial metabolites in environmental samples and their associations with respiratory health and disease.
3. Elucidation of the mechanisms through which environmental microbiomes and their metabolites modulate the immune system, promote inflammation, or contribute to respiratory disease pathogenesis.
4. Examination of the interactions between environmental microbiomes and human-associated microbiomes (e.g., respiratory and gut microbiomes) in the context of respiratory health and disease.
5. Development and application of novel experimental models, computational approaches, and analytical techniques for studying environmental microbiomes, metabolites, and respiratory diseases.
6. Assessment of the potential therapeutic or preventative strategies targeting environmental microbiomes and their metabolites to improve respiratory health.
By fostering interdisciplinary research and collaboration, this special issue collection aims to advance our understanding of the relationships between environmental microbiomes, their metabolites, and respiratory diseases. Ultimately, the insights gained from these studies may inform the development of novel strategies for the prevention, diagnosis, and treatment of respiratory diseases, thereby improving public health and reducing the burden on healthcare systems.
Keywords: Environmental microbiomes, indoor and outdoor environments, respiratory diseases, microbial metabolites, respiratory microbiome
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.