Prediabetes - Early Interventions and Prevention in Insulin Resistance

Prediabetes affects about 10-15% of the adult population and is defined as an intermediate hyperglycemic state with glucose levels above normal, but not meeting the diagnostic criteria for diabetes. It is estimated that in 70% of those affected, prediabetes progresses to overt type 2 diabetes during their lifetime, and even in those who remain prediabetic, it increases the risk of serious micro- and macrovascular complications, worsening overall quality of life. However, several studies have shown that the prediabetic state is reversible. The management/treatment of prediabetes is based on lifestyle modification, including dietary interventions and increased physical activity. Nevertheless, recent literature indicates that there are different approaches to diet in the management of prediabetes and long-standing debates about the amount of exercise to be combined with dietary modifications. The current research topic focuses on perspectives on lifestyle and pharmacological interventions in the management of prediabetes.

Although the adverse health effects of prediabetes are clear, guidelines for its management are still not established. This is because the available clinical evidence on the management of prediabetes is still limited. Therefore, there is a need to evaluate the effectiveness of various lifestyle intervention programs and drug treatment in the management of prediabetes. The purpose of this Research Topic is to compile the results of studies on the prevention and treatment of prediabetes, which would help to evaluate the effectiveness of various intervention methods and, more broadly, to formulate guidelines for the management of this condition.

Potential topics include, but are not limited to:

• New lifestyle approaches in the treatment/management of prediabetes
• Different types of diets used in the treatment/management of prediabetes
• Different types of exercise used in the treatment/management of prediabetes
• The role of traditional diet and foods in the treatment of prediabetes
• The effects of various compounds/dietary supplements in the treatment/management of prediabetes
• Interdisciplinary advances in the treatment/management of prediabetes
• The use of supplementary strategies in the treatment and prevention of prediabetes (including new/natural compounds)

We invite you to submit short research reports, original studies, clinical trials, research cases, full or mini-reviews, general comments, opinions, or perspectives. We hope you will consider our Research Topic as a venue for disseminating the latest research findings in this field.