About this Research Topic
The goal of this article collection is to provide a comprehensive understanding of the endocrine and cardiometabolic complications of obesity in children and explore the possibilities for reversing them in both the short and long-term observation periods.
We welcome submissions covering the following sub-areas:
Endocrine complications: Hormonal changes that occur in obese children and how they contribute to the development of complications such as insulin resistance and type 2 diabetes. We encourage investigations into the role of adipose tissue and its interaction with hormones such as insulin, leptin, and adiponectin in the development of these complications.
Cardiometabolic complications: The impact of obesity on cardiovascular health in children. We welcome studies that explore the link between obesity, inflammation, and the development of cardiovascular diseases such as hypertension and atherosclerosis. We also encourage investigations into the effect of obesity on lipid metabolism and its contribution to the development of dyslipidemia.
Reversal strategies: The effectiveness of different interventions in reversing the endocrine and cardiometabolic complications of obesity in children. We welcome studies that examine the impact of lifestyle interventions such as diet and exercise, as well as pharmacological interventions such as metformin, in improving insulin sensitivity and reducing the risk of type 2 diabetes. Additionally, we encourage investigations into the impact of weight loss on cardiovascular health and the potential benefits of bariatric surgery in severely obese children.
In conclusion, we hope that this article collection will provide new insights into the endocrine and cardiometabolic complications of obesity in children and identify effective strategies for preventing or reversing them. We encourage authors to submit original research, reviews, and meta-analyses in these areas to contribute to the growing body of knowledge on this important topic.
Keywords: childhood obesity, obesity reversal, cardiometabolic complications of obesity, endocrine complications of obesity, obesity monitoring
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.