Frontiers in Cell and Developmental Biology is delighted to present the ‘Reviews and Advances in’ series of article collections.

Membrane trafficking is a critical area of research within cell and developmental biology, particularly due to its essential role in maintaining the functions of eukaryotic cells. Defects in these pathways are increasingly recognized as significant contributors to various pathologies, including cancer. Recent studies have highlighted the intricate molecular mechanisms by which membrane trafficking influences tumor cell growth and progression. Despite these advances, there remain substantial gaps in our understanding of how these processes are regulated and their broader implications in cancer biology. Ongoing debates focus on the specific roles of intracellular trafficking in cancer cell proliferation, invasion, and metastasis, as well as the interplay between membrane transport and cytoskeletal dynamics. There is a pressing need for further investigation to unravel these complex interactions and to identify potential therapeutic targets.

This research topic aims to explore the molecular mechanisms underlying membrane trafficking in cancer, with a focus on tumor cell growth and progression. The objective is to consolidate recent advances in the field, address existing knowledge gaps, and propose new directions for future research. Key questions include how intracellular trafficking contributes to cancer cell proliferation and invasion, and the role of specific organelles and vesicle transport systems in these processes. By encouraging contributions from early-career researchers and emerging independent investigators, this collection seeks to foster innovative approaches and fresh perspectives in the field.

To gather further insights into the intricate dynamics of membrane trafficking in cancer, we welcome articles addressing, but not limited to, the following themes:
- The role of intracellular trafficking in cell proliferation, epithelial to mesenchymal transition, and invasion
- The interplay between membrane transport and cytoskeleton dynamics
- The involvement of cancer receptors, the Endoplasmic Reticulum, and mitochondria
- Vesicle transport mechanisms contributing to tumor cell growth
- The role of caveolae in cancer progression
- Control of inter-organelle interactions by tumor suppressor proteins

This collection aims to provide a comprehensive overview of current research and stimulate further exploration in this vital area of cancer biology.

We accept different article types including Mini-Reviews, Brief Research Reports and Perspectives. A full list of accepted article types, including descriptions, can be found at this link.

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