About this Research Topic
COVID-19 swiftly spread across the globe, by February 24, 2023, 64.7 million people had contracted SARS-CoV-2, and 6.868 million of them are reported to have perished from the disease or other serious systemic complications. Increasing evidence has raised concerns about the ocular complications caused by SARS-CoV-2 or COVID-19 vaccination. The reported ocular manifestations due to COVID-19 vary greatly and include dry eye, conjunctivitis, scleritis, uveitis, endophthalmitis, retinopathy and retinal vascular occlusions, acute glaucoma, optic neuropathy, and cranial nerve palsies. Likewise, COVID vaccination has been reported to be associated with an increased risk of uveitis, retinal vascular occlusions, optic neuritis, and possibly corneal transplant rejection. The underlying mechanisms of pathogenesis of many of these sequelae remain poorly understood. As the pandemic continues to evolve with new viral variants, and likewise new vaccines to answer these challenges, all aspects of these potential sequelae need to be appreciated and understood. Furthermore, the eyes may serve as a window to various systemic diseases, and a thorough understanding COVID-19 associated ocular complications can also inform the diagnosis and management of COVID-19 systemic disease and its sequelae.
This Research Topic aims to examine the wide spectrum of ocular sequelae and to address the latest advancements in scientific and clinical principles for the diagnosis, progression, and management, for individuals with COVID-19 or vaccination-associated ocular complications. We aim to emphasize the importance of collaboration and communication among the interprofessional team to improve clinical outcomes for patients affected by COVID-19.
In this Research Topic, we will welcome case reports, original research, meta-analyses, and review articles, to address the etiology, pathophysiology, diagnosis, imaging, cellular and molecular biomarkers, and management. Subtopics include, but are not limited, to the following:
• The epidemiology of COVID-19 or vaccination-associated ocular complications
• The pathophysiology and underlying mechanisms of these diseases
• Novel diagnostic tools for early diagnosis and its consequences of the COVID-19 complications: biomarkers and imaging
• Prognostic models for COVID-19 ocular complications
• Therapeutic approaches for these disorders
• The impact of the COVID-19 pandemic on clinic appointments or presentations, and on ocular surgery, including cosmetic surgery
This Research Topic aims to examine the wide spectrum of ocular sequelae and to address the latest advancements in scientific and clinical principles for the diagnosis, progression, and management, for individuals with COVID-19 or vaccination-associated ocular complications. We aim to emphasize the importance of collaboration and communication among the interprofessional team to improve clinical outcomes for patients affected by COVID-19.
In this Research Topic, we will welcome case reports, original research, meta-analyses, and review articles, to address the etiology, pathophysiology, diagnosis, imaging, cellular and molecular biomarkers, and management. Subtopics include, but are not limited, to the following:
• The epidemiology of COVID-19 or vaccination-associated ocular complications
• The pathophysiology and underlying mechanisms of these diseases
• Novel diagnostic tools for early diagnosis and its consequences of the COVID-19 complications: biomarkers and imaging
• Prognostic models for COVID-19 ocular complications
• Therapeutic approaches for these disorders
• The impact of the COVID-19 pandemic on clinic appointments or presentations, and on ocular surgery, including cosmetic surgery
Keywords: COVID-19, ocular complications, pathogenesis, vaccination, SARS-CoV-2
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
