About this Research Topic
This topic will focus on multiple facets of tumor heterogeneity, spanning from genetic changes during tumor progression to changes in the cellular complexity of the tumor microenvironment. We will also focus on the progress in different technologies that provide deeper insights into cancer genetics and cellular heterogeneity and how the comprehensive characterization of various cell populations and their interplay in the tumor ecosystem, influences the development of novel and personalized therapeutic strategies.
The editors welcome various article types (including Mini-Reviews and Brief Research Reports) focusing on but not limited to:
• New/improved technological advances to explore tumor heterogeneity;
• Reviews/Mini-Reviews summarizing/discussing cutting-edge technologies that explore heterogeneity in tumor genetics/microenvironment or provide prospective technological directions;
• Original Research/Brief Research Reports exploring the basic/important questions pertaining to tumor heterogeneity;
• Original Research/Brief Research Reports on clinical diagnosis/treatment involving tumor genetics/microenvironment.
More information on article types accepted by the journal can be found here.
Please note: Descriptive studies consisting solely of bioinformatic investigation of publicly available genomic/transcriptomic/proteomic data do not fall within the scope of the section unless they are expanded and provide significant biological or mechanistic insight into the process being studied.
Keywords: technological advances, cancer heterogeneity, single cell analysis, tumor cell microenvironment, tumor heterogeneity, tumor genetics
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.