Frontiers | Exploring the Impact of Genetics on New Drugs and Potential Drug Targets: A Multi-Omics Approach to Improve Personalized Therapeutics.

Exploring the Impact of Genetics on New Drugs and Potential Drug Targets: A Multi-Omics Approach to Improve Personalized Therapeutics.

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ORIGINAL RESEARCH

Published on 17 Apr 2024

Identification of pivotal genes and regulatory networks associated with atherosclerotic carotid artery stenosis based on comprehensive bioinformatics analysis and machine learning

Xiaohong Qin
Rui Ding
Haoran Lu
Wenfei Zhang
Shanshan Wei
Baowei Ji
Rongxin Geng
Liquan Wu
Zhibiao Chen

doi 10.3389/fphar.2024.1364160

1,283 views

ORIGINAL RESEARCH

Published on 31 Jan 2024

Racial disparities in metastatic colorectal cancer outcomes revealed by tumor microbiome and transcriptome analysis with bevacizumab treatment

Lei Feng
Rui Wang
Qian Zhao
Jun Wang
Gang Luo
Chongwen Xu

doi 10.3389/fphar.2023.1320028

1,196 views
1 citation

REVIEW

Published on 09 Jan 2024

Machine learning in onco-pharmacogenomics: a path to precision medicine with many challenges

Alessia Mondello
Michele Dal Bo
Giuseppe Toffoli
Maurizio Polano

doi 10.3389/fphar.2023.1260276

3,202 views
4 citations

ORIGINAL RESEARCH

Published on 03 Jan 2024

Transcriptomic and metabolomic analysis of peri-tumoral hepatic tissue in hepatocellular carcinoma: unveiling the molecular landscape of immune checkpoint therapy resistance

Huaqiang Bi
Kai Feng
Xiaofei Wang
Ping Zheng
Chengming Qu
Kuansheng Ma

doi 10.3389/fphar.2023.1304996

969 views

ORIGINAL RESEARCH

Published on 14 Sep 2023

Elucidating the molecular mechanisms of ozone therapy for neuropathic pain management by integrated transcriptomic and metabolomic approach

Xiaolan Yang
Chaoming Chen
Keyang Wang
Min Chen
Yong Wang
Zhengping Chen
Wang Zhao
Shu Ou

doi 10.3389/fgene.2023.1231682

2,094 views
1 citation

ORIGINAL RESEARCH

Published on 28 Aug 2023

Investigating Doxorubicin’s mechanism of action in cervical cancer: a convergence of transcriptomic and metabolomic perspectives

Zhuo Huang
Huining Jing
Juanjuan Lv
Yan Chen
YuanQiong Huang
Shuwen Sun

doi 10.3389/fgene.2023.1234263

1,952 views
3 citations

REVIEW

Published on 24 Aug 2023

The impact of gene polymorphism and hepatic insufficiency on voriconazole dose adjustment in invasive fungal infection individuals

Guolin Li
Qinhui Li
Changji Zhang
Qin Yu
Qi Li
Xiaoshi Zhou
Rou Yang
Xuerong Yang
Hailin Liu
Yong Yang

doi 10.3389/fgene.2023.1242711

2,485 views
3 citations

ORIGINAL RESEARCH

Published on 08 Jun 2023

Unraveling the therapeutic mechanisms of dichloroacetic acid in lung cancer through integrated multi-omics approaches: metabolomics and transcriptomics

Malong Feng
Ji Wang
Jianying Zhou

doi 10.3389/fgene.2023.1199566

2,522 views
4 citations

REVIEW

Published on 26 May 2023

Ferroptosis and multi-organ complications in COVID-19: mechanisms and potential therapies

Qi Li
Zeyuan Chen
Xiaoshi Zhou
Guolin Li
Changji Zhang
Yong Yang

doi 10.3389/fgene.2023.1187985

4,406 views
11 citations

CASE REPORT

Published on 20 Apr 2023

Case report: A case study on the treatment using icaritin soft capsules in combination with lenvatinib achieving impressive PR and stage reduction in unresectable locally progressive pancreatic cancer and a literature review

Xiaolong Liu
Feimin Yang
Dunmao Jia
Xinyu Dong
Yizhuo Zhang
Zhengrong Wu

doi 10.3389/fgene.2023.1167470

1,561 views
3 citations

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Pharmacogenetics and Pharmacogenomics

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Frontiers in Pharmacology
- Pharmacogenetics and Pharmacogenomics
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Articles

Identification of pivotal genes and regulatory networks associated with atherosclerotic carotid artery stenosis based on comprehensive bioinformatics analysis and machine learning

Racial disparities in metastatic colorectal cancer outcomes revealed by tumor microbiome and transcriptome analysis with bevacizumab treatment

Machine learning in onco-pharmacogenomics: a path to precision medicine with many challenges

Transcriptomic and metabolomic analysis of peri-tumoral hepatic tissue in hepatocellular carcinoma: unveiling the molecular landscape of immune checkpoint therapy resistance

Elucidating the molecular mechanisms of ozone therapy for neuropathic pain management by integrated transcriptomic and metabolomic approach

Investigating Doxorubicin’s mechanism of action in cervical cancer: a convergence of transcriptomic and metabolomic perspectives

The impact of gene polymorphism and hepatic insufficiency on voriconazole dose adjustment in invasive fungal infection individuals

Unraveling the therapeutic mechanisms of dichloroacetic acid in lung cancer through integrated multi-omics approaches: metabolomics and transcriptomics

Ferroptosis and multi-organ complications in COVID-19: mechanisms and potential therapies

Case report: A case study on the treatment using icaritin soft capsules in combination with lenvatinib achieving impressive PR and stage reduction in unresectable locally progressive pancreatic cancer and a literature review

Frontiers in Genetics

Participating Journals

Impact