About this Research Topic
Enteroviruses are pathogens that can cause a range of human diseases, and the genus Enterovirus consists of 15 species, including Enterovirus A-L and Rhinovirus A-C. Notably, Enterovirus A71 (EV-A71) and coxsackievirus A16 (CV-A16) are significant infectious agents responsible for hand, foot, and mouth disease (HFMD), which can lead to severe neural complications. The majority of HFMD outbreaks have been reported in the Asia-Pacific region, including countries such as Malaysia, Vietnam, China, and India. Despite the implementation of vaccination and public health interventions, enteroviruses continue to circulate in this region. A critical gap in the current state of knowledge is the lack of specific antiviral drugs against EV-A71, with clinical treatment remaining largely supportive. Understanding the host-enterovirus relationship and the underlying pathogenic mechanisms is crucial for elucidating the viral pathogenesis of RNA viruses. Additionally, other enteroviruses, such as Enterovirus D68 (EV-D68), have caused significant outbreaks and are associated with severe respiratory symptoms and acute flaccid myelitis in children. This highlights the need for a deeper investigation into the molecular mechanisms of enteroviral infections and the development of effective therapeutic strategies.
This research topic aims to explore the molecular mechanisms of viral pathogenesis, identify host factors involved in enteroviral infections, and develop new detection methods and antiviral therapies for enteroviruses. By addressing these objectives, the research seeks to answer critical questions about the host-pathogen interactions and the development of effective treatments for enteroviral diseases.
To gather further insights into the host-enterovirus relationship and the pathogenic mechanisms of enteroviruses, we welcome articles addressing, but not limited to, the following themes:
- Molecular mechanisms of enteroviral pathogenesis
- Host factors involved in enteroviral infections
- Development of new detection methods for enteroviruses
- Advances in antiviral therapies for enteroviruses
- Epidemiological studies of enteroviral outbreaks in the Asia-Pacific region
- Clinical management and treatment strategies for enteroviral infections
- Comparative studies of different enterovirus species and their pathogenicity
This research topic aims to explore the molecular mechanisms of viral pathogenesis, identify host factors involved in enteroviral infections, and develop new detection methods and antiviral therapies for enteroviruses. By addressing these objectives, the research seeks to answer critical questions about the host-pathogen interactions and the development of effective treatments for enteroviral diseases.
To gather further insights into the host-enterovirus relationship and the pathogenic mechanisms of enteroviruses, we welcome articles addressing, but not limited to, the following themes:
- Molecular mechanisms of enteroviral pathogenesis
- Host factors involved in enteroviral infections
- Development of new detection methods for enteroviruses
- Advances in antiviral therapies for enteroviruses
- Epidemiological studies of enteroviral outbreaks in the Asia-Pacific region
- Clinical management and treatment strategies for enteroviral infections
- Comparative studies of different enterovirus species and their pathogenicity
Keywords: Enterovirus, Rhinovirus, Pathogenesis, Host factors, Virus detection, Vaccine Antiviral
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
