Soft materials as a promising candidate for human-machine interface provide unprecedented opportunities to the fields from biology and translational medicine to bioelectronics and personal healthcare. Soft materials have played important roles in providing advanced diagnoses and therapies. However, the field still exposes many scientific and technological challenges. Insufficient scientific understandings and inadequate technology limit the development of advanced soft materials in biomedical engineering. Soft materials' fabrication and processing techniques (e.g., laser cutting, UV lithography, 3D-printing, spin coating, and electrospinning) are essential to realizing functional structures for biological applications, including tissues repair, haemostats, surgical tape/glues, biomedical devices, etc.

This Research Topic focuses on the most recent advances in techniques and methodologies for developing multifunctional soft materials, such as design, synthesis, characterization, manufacturing, and theoretical analysis to solve critical challenges in engineering and medicine. Therefore, original research articles (full papers and short communications), reviews, mini-reviews, perspectives, and opinions covering the latest studies and progress are highly welcomed.

We welcome submissions covering the following themes, but are not limited to:

• Functional soft materials/devices for advanced therapy and diagnosis

• Novel engineering approaches for developing clinically relevant soft materials, such as microfluidics, three-dimensional printing, and electrospinning

• Development of printable tissue adhesives and hydrogel-based bioinks for tissue repairs

• Innovative 3D printing methods and new bioinks to create tissue mimics for disease modeling, drug release model and therapeutic

• Understanding the interface between soft materials and biological tissue

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Frontiers in Bioengineering and Biotechnology

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