This is Volume II of the Research Topic "Interactions between Bioactive Food Ingredients and Intestinal Microbiota". The previous edition can be found here.

Numerous microorganisms colonize the gastrointestinal tract playing critical roles concerning digestion and absorption of dietary nutrients and the regulation of important functions, including host metabolism, immunity, and intestinal barrier function. Increasing evidence suggests that food encompassing nutrients and polyphenols are strong drivers shaping the composition and function of the gut microbiota and mediate the host's physiological activities directly or indirectly. However, the mechanisms involved in the interactions between food nutrients/prebiotics, gut microbiota and host health have not been enlightened to a wide extent.

In this Research Topic, manuscripts focusing on the nutrient-gut microbiota interaction, its role in the development of dysbiosis (imbalance) and low-grade inflammation during the intestinal barrier dysfunction and metabolic disorders are especially welcome. Understanding the molecular mechanisms that regulate gut microbiota and its metabolic activity by dietary nutrients may be useful in developing dietary approaches to improve human health via a precision microbiome modulation. We hope to attract both research and review articles that contribute to and describe the field's current status, respectively.

Potential topics include but not limited to the following:

• Modulation of gut microbiome composition and function by food nutrients in metabolic disorders or inflammation-related intestinal diseases
• The possible mechanisms for the microbial metabolites derived from dietary in mediating host physiological activities
• The microbe-microbe interactions in the face of nutritional intervention, including microbial communication and signalling
• Crosstalk among diet, gut microbiota and gut health/host metabolism
• Development of nutritional strategies to precisely modulate gut microbiome and gut health

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Frontiers in Microbiology

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