About this Research Topic
Inflammatory bowel disease (IBD) is a chronic inflammatory disease as a result of a dysregulated immune response caused by a combination of environmental and genetic factors. The main challenges are the lack of a comprehensible understanding of the inflammatory process and how to detect prognostic and predictive factors for therapeutic approaches at the onset and during the course of the disease.
IBD represents a complex interaction within various biological systems. The goal of this study is to develop a review of the state of the art of systems biology in the context of integrating available transomic IBD data and future aspects of this scientific approach.
A team of international scientists will give an overview of their respective research fields including genetics, epigenetics, proteomics, metabolomics/lipidomics, immunohistochemistry, multimodal molecular imaging, and finally transomics analyses. Based on this set of transomic knowledge the goals of the study will be performed.
At least two review articles have been planned- one on the pathophysiology of IBD and one on predictive and prognostic biomarkers of IBD.
The study will give new interpretations of available data and most likely be beyond the-state-of-the-art of IBD with a special focus on precision medicine in IBD which is one of the most important frontiers in IBD research.
IBD represents a complex interaction within various biological systems. The goal of this study is to develop a review of the state of the art of systems biology in the context of integrating available transomic IBD data and future aspects of this scientific approach.
A team of international scientists will give an overview of their respective research fields including genetics, epigenetics, proteomics, metabolomics/lipidomics, immunohistochemistry, multimodal molecular imaging, and finally transomics analyses. Based on this set of transomic knowledge the goals of the study will be performed.
At least two review articles have been planned- one on the pathophysiology of IBD and one on predictive and prognostic biomarkers of IBD.
The study will give new interpretations of available data and most likely be beyond the-state-of-the-art of IBD with a special focus on precision medicine in IBD which is one of the most important frontiers in IBD research.
Keywords: IBS, inflammatory bowel disease, molecular medicine, biology, pathophysiology, biomarkers
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
