About this Research Topic

Background

Cow's milk protein allergy is one of the most frequent food allergies and the most frequent in infants, representing a high cost. The pathophysiology of IgE-mediated cow’s milk protein allergy has been studied but we know little about non IgE-mediated allergy. This makes it difficult to have a sensitive and specific biomarker for diagnosis. Regarding treatment, we know that a cow's milk protein exclusion diet is the gold standard. However, oral tolerance time may still be controversial, implying the prolongation of expensive formulas or prolonged diets for the mother and the patient.

This Research Topic has three major goals:
1. Know the pathophysiology of cow´s milk protein allergy, both IgE mediated and non IgE mediated.
2. Know the mechanism of oral tolerance in cow’s milk protein allergy.
3. Describe cutting-edge treatments of cow’s milk protein allergy.

We welcome all article types accepted by Frontiers in Allergy. Suitable themes for manuscripts include, but are not limited to:

• Epidemiology of cow's milk protein allergy
• Natural history of cow's milk protein allergy and atopic march
• Pathophysiology of cow's milk protein allergy (IgE mediated and non IgE mediated)
• Cow's milk allergy and skin disorders
• Cow's milk allergy and digestive system disorders
• Mechanism of oral tolerance in cow's milk protein allergy
• Cutting edge treatment of cow's milk allergy
• Nutrition and immunotherapy in cow's milk allergy
• Guidelines for management of cow's milk protein allergy in different countries

Keywords: protein, allergy, cow's milk, Ige mediated, non IgE mediated

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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