About this Research Topic
The gut microbiota has been demonstrated to play a critical role in regulating mental disorders via the gut-brain axis, however, the exact mechanism remains to be determined. There is still much to investigate about the physiological mechanism of obesity and gut-brain axis and its effect on appetite, eating behaviors, and other physiological mechanisms of the body. The gut-brain axis plays a key role in energy homeostasis of the body, and is becoming a hot topic of research, but little study has been addressed regarding the molecular pathways in the context of disorders of the gut-brain axis due to obesity.
The primary aim of the Research Topic is to seek high-quality contributions that address these points above. The article types including Original Research, Reviews, and Mini Review are welcome. We strongly encourage the submissions focusing on topics of interest that include but are not limited to the following:
• Examination of the gut microbiota and intestinal microbial metabolites in regulating host metabolism, and central appetite through the gut-brain axis.
• Examination of gut dysbiosis and regional immune activation and its link to mental disorders
• The effect of gut microbiota and healthy gut function on depression, anxiety, and cognitive functions.
• Omics analysis of gut microbiota in relation to obesity-associated CNS disorders
• Studies on the application of emerging data mining and machine learning techniques in gut-brain axis physiology and pathology.
Keywords: gut-brain axis, obesity, metabolic diseases, metabolism, microbiome
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.