With the social economy developing, people put forward high demands for high-quality oral healthcare, which requires the development of biomaterials and technologies in dentistry. In particular, the aging of the population leads to an increasing number of people suffering tooth loss, bone fractures, or bone defects caused by periodontitis, tumor, trauma, or degenerative diseases. Over the past two decades, conventional therapeutic strategies, including dental implants, bone grafting, and guided tissue regeneration, have been developed to address the clinical challenges. However, bone-implant osseointegration or soft/hard integrated regeneration still needs to be improved for a better outcome. Advanced biomaterials and technologies in oral and maxillofacial surgery, implantology, periodontics, and prosthodontics should be paid greater attention to and explored more.

In recent years, various advanced biomaterials (e.g., bioactive ceramics/glasses, biodegradable metals, piezoelectric materials, self-healing hydrogels/elastomers, 2D nanomaterials) and technologies (e.g., additive manufacturing, stem cells, gene/growth factors delivery, surface modification, surface pattern, pore topology) have emerged and attracted extensive interest from worldwide researchers in biomaterials, biomedical engineering, and stomatology. Therefore, this research topic aims to collect the latest and innovative biomaterials and technologies for oral and maxillofacial regeneration, focusing on cutting-edge ideas and exploring novel dental biomaterials/techniques in advancing this topic.

The Research Topic welcomes contributions from multi-disciplinary research. We cordially invite authors to contribute original research articles, reviews, and bioinformatics-analysis research articles that are focused on, but not limited to, the following areas:

1. Advanced biomaterials in the regeneration of maxillofacial and periodontal bone defects
2. Novel biomaterials and technologies for tooth regeneration
3. Novel biomaterials and technologies for guided bone and tissue regeneration membranes
4. Surface modifications of dental implants Biomaterials for tooth, periodontal and maxillofacial bone tissue engineering
5. Gene therapeutic strategy for tooth, periodontal and maxillofacial bone regeneration
6. Stem cells therapeutic strategy for tooth, periodontal and maxillofacial bone regeneration
7. Biocompatibility evaluation of dental biomaterials
8. Regenerative biomaterials and technologies: future trends in tooth, periodontal and maxillofacial bone regeneration

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