Allergy and Metabolic Disorders and its Link to the Gut Microbiome

Recent studies have implicated that allergic diseases are associated with metabolic disorders. However, more studies are warranted to confirm this link and elucidate the potential mechanism. Accumulating evidence indicates that the gut microbiome plays a critical or even a causative role in the development of inflammatory diseases including allergy and metabolic diseases. Perturbed gut microbiome and subsequent induction of inflammatory immune responses might explain the relationship between allergy and metabolic disorders. The study of gut-host interactions and mechanisms in disease development is an emerging field with high potential for improving human health.

The objective of this Research Topic is to collate a series of reviews, meta-analysis, commentaries, and research articles on the relationship between allergic diseases (food allergy, eczema, allergic rhinitis, or asthma) and metabolic disorders, and the role of the gut microbiome in this link.

Suitable themes for manuscripts include:

• Relationship between allergic diseases and metabolic disorders
• Role of the gut microbiome in the link between allergy and metabolic disorders
• Metagenomics, metabolomics, proteomics, or meta transcriptomics in the study of the relationship between the gut microbiome, allergy, and metabolic disorders
• Targeting the gut microbiome to prevent or treat allergic diseases and metabolic disorders
• Effect of anti-allergy drugs on the gut microbiome and host metabolic status

Keywords: Atopic dermatitis, Food Allergy, Asthma, Allergic rhinitis, Gut microbiome, Metabolic disorder, Metabolome, Probiotics, Prebiotics

Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.