The gut microbiota not only plays important roles in many metabolic pathways, but it also provides the host with a variety of functions that promote immune homeostasis, immune responses, and prevent pathogen colonization. The gut microbiota, as well as their metabolites and components, are required for immune homeostasis and influence host susceptibility to a wide range of immune-mediated diseases and disorders. The composition of the gut microbiota influences immune system development and modulates immune mediators, which in turn affects the function of the intestinal barrier.

To this end, This Research Topic aims to present and discuss the most recent evidence on the role of nutritional strategies in regulating gut microbiota and host immune system, which will assist in understanding how nutritional strategies can promote immunity homeostasis and intestinal barrier function via the gut microbiota.

This Research Topic aims to collect publications on pig nutrition in particular, but studies involving other animals that address the relevant issues are also welcome.

We are delighted to announce the call for papers for this Research Topic on recent advances in gut microbiota, the host immune system and intestinal barrier function. Both Reviews and Original Research articles will be considered for this Research Topic. Submission of papers focusing on the following research areas is strongly encouraged:
• The crosstalk between microbiota, host intestinal immune system and the intestinal barrier function;
• Molecular pathways of immune modulation by gut microbiota and its’ metabolites;
• The nutritional strategies and interventions modulating microbiota composition and function;
• The nutritional strategies and interventions modulating microbiota, host intestinal immune system and the intestinal barrier function.

Please note that Systems Microbiology does not consider descriptive studies that are solely based on amplicon (e.g., 16S rRNA, 18SrRNA, ITS and other marker genes) profiles.

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Frontiers in Microbiology

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