About this Research Topic
Recently, the placenta, a key organ during pregnancy, has emerged as a major target of study due to gestational alterations than can produce adverse gestational outcomes in the fetus. Both pregnancy and obesity are conditions where an inflammatory environment occur, producing ROS and several physiological alterations. However, an excess of ROS production can develop several adverse consequences, promoting in this sense placental alterations in its structure and function. For this reason, it is important to know how this oxidative stress environment is affecting placental and, hence, fetal development, in order to address the growing need to reverse a condition that has become a pathology in humanity, such as obesity. This cycle can become even more vicious if drug use comes into play.
Topics of interest are, but not limited to:
• Understanding obesity and its complications on mother and child.
• Placental alterations in obesity pregnancies.
• Oxidative stress environment and its impact in placental/fetal development.
• Diagnostic and predictive biomarkers for obesity and placental alterations.
Keywords: Obesity, reactive oxygen species (ROS), placenta
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