About this Research Topic
Co-infection is the simultaneous infection of a host with multiple pathogen species. Many human pathogens (e.g., viruses, bacteria, protozoa, fungal parasites, helminths) often co-infect an individual. An example of common co-infection involves Mycobacterium tuberculosis and HIV. In some countries, nearly 80% of tuberculosis patients are co-infected with HIV, which further contributes to the deterioration of patient health status compared to single pathogen infection. Some prevalent diseases, including COVID-19, AIDS, tuberculosis, malaria, hepatitis, leishmaniasis, and dengue fever, may be profoundly affected by the co-infection with multiple pathogens threatening human health.
Co-infection is of particular importance since coinfecting pathogens can interact with each other either directly or indirectly via the host immune system. Moreover, compared to the infection of single pathogen species, the interactions between different pathogens within co-infected hosts can alter the transmission, clinical progression, and consequences of control of multiple infectious diseases. Therefore, understanding co-infection prevalence and subsequent consequences is greatly needed to explore the treatment strategy. However, determining the mechanism and consequences of co-infection requires comprehensive surveillance and research of different infectious diseases.
Thus, we will collect the basic and clinical research papers focusing on the mechanism and consequences of virus or other pathogens co-infection, aiming to provide insightful information and reveal the potential mechanism to facilitate the development of infectious disease treatment.
This research topic will incorporate recent findings on the interaction between host and coinfecting viruses or other pathogens, the impact of co-infection on clinical outcomes, the molecular mechanisms of co-infections in infectious diseases or cancers, and the potential treatment strategy for infectious disease.
Types of manuscripts: all perspective articles include but are not limited to Original Research Articles, Review, Mini review and Hypothesis, Theories, etc.
The following diseases involved in co-infection are all in particular welcome
• Tuberculosis
• Acquired immunodeficiency syndrome (AIDS)
• Hepatitis
• Nasopharyngeal carcinoma
• Lymphoma
• Cervical cancer
• Coronavirus infection
• Co-infected other viral zoonotic diseases
Co-infection is of particular importance since coinfecting pathogens can interact with each other either directly or indirectly via the host immune system. Moreover, compared to the infection of single pathogen species, the interactions between different pathogens within co-infected hosts can alter the transmission, clinical progression, and consequences of control of multiple infectious diseases. Therefore, understanding co-infection prevalence and subsequent consequences is greatly needed to explore the treatment strategy. However, determining the mechanism and consequences of co-infection requires comprehensive surveillance and research of different infectious diseases.
Thus, we will collect the basic and clinical research papers focusing on the mechanism and consequences of virus or other pathogens co-infection, aiming to provide insightful information and reveal the potential mechanism to facilitate the development of infectious disease treatment.
This research topic will incorporate recent findings on the interaction between host and coinfecting viruses or other pathogens, the impact of co-infection on clinical outcomes, the molecular mechanisms of co-infections in infectious diseases or cancers, and the potential treatment strategy for infectious disease.
Types of manuscripts: all perspective articles include but are not limited to Original Research Articles, Review, Mini review and Hypothesis, Theories, etc.
The following diseases involved in co-infection are all in particular welcome
• Tuberculosis
• Acquired immunodeficiency syndrome (AIDS)
• Hepatitis
• Nasopharyngeal carcinoma
• Lymphoma
• Cervical cancer
• Coronavirus infection
• Co-infected other viral zoonotic diseases
Keywords: co-infection, virus, HIV, tuberculosis, humans
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
