Intraparenchymal hemorrhage (IPH) due to vascular malformation still represents a significant cause of morbidity and mortality throughout the world in which outcome can be dramatically impacted by early and expert care. The role of the vein in these pathologies in still unknown.

Vascular malformation associated with arteriovenous shunts between the Dural/epidural artery and Dural vein and/or Dural venous sinus, can cause various symptoms, and the risk of aggressive symptoms such as cerebral hemorrhage and venous infarction mainly depends on venous drainage patterns in patients. Patients with cortical venous reflux have a high risk of aggressive symptoms due to cerebral venous congestion or varix rupture, and they often develop brain edema and/or hemorrhage. The management of vascular malformation is a multidisciplinary complex undertaking and, the current state of knowledge is in rapid evolution. Considerable advances have been made in diagnostic methods, surgical and endovascular techniques and clinical management paradigms. Intraparenchymal hemorrhage is still a relevant health problem and, although its incidence varies among population, a quarter of patients affected by IPH due to vascular malformation die and approximately half of survivors are left with some persistent neurological deficit.

Taking into account the fact that the prognosis of patients is affected by multiple factors and that some of them can be influenced by therapeutic strategies and management procedures we believe that there is a need to reassess which interventions provide the greatest benefit to patients.

Seeing veins in the brain is like saying clouds in the sky. From the presence of clouds in the sky, from their shape, their color, their quantity, we can predict if it will rain, snow, hail or if there will be good weather.

This special issue for Frontiers in Neurosurgery will deal with brain pathologies in which the veins are involved.

The number of veins, the shape and location in an arteriovenous malformation may be related to the difficulty of treatment, the likelihood of bleeding, and the possibility of reaching the malformation nidus through the veins.

DVA related to cavernomas may also play a role in the genesis of cavernoma, must be spared, and may be connected with a different prognosis. Dural arteriovenous fistulas can be treated through the veins and have a different risk of bleeding based on the type of vein involved.

Venous malformations and telangiectasias are pathologies of which little is known from a clinical and prognostic point of view.
Venous thrombosis and other pathologies of the veins can be of great neurosurgical interest. All scientific work involving pathologies related to the cerebral veins is welcome.

The aim of this special issue will be to gather publications that focus on the progress and update of management paradigms and therapeutic modalities to assist clinicians in the day to day multidisciplinary management of vascular malformations.

Type of accepted manuscripts:
-Original research
- Literature review and Metanalysis

Submit your idea

Impact

Frontiers in Surgery

Impact