Hypersomnolence is a disabling symptom manifesting as excessive daytime sleepiness and/or excessive need for sleep and often includes other cognitive complaints (impaired vigilance, altered attention, poor memory, emotional difficulties, etc.). The socio-economic burden of hypersomnolence is high and is associated with increased health-related medical referrals, higher expenses, and medication use, as well as increased risk of accidents. A number of clinical conditions and pathologies can result in hypersomnolence with an additional impact of chronic sleep deprivation, circadian disorders, sleep-disordered breathing and others. Hypersomnolence is a specific symptom of the central disorders of hypersomnolence including narcolepsy and idiopathic hypersomnia, which present as heterogenous entities. Hypersomnolence is also a frequent co-morbidity in a variety of medical, neurological, and psychiatric diseases.

The goal of this Research Topic is to increase awareness about the problems associated with hypersomnolence disorders, and to bring attention to their heterogeneity as well as their impact and interaction with the wide spectrum of internal diseases. The article collection will also present the recent advances in the field including the current understanding of the underlying neurobiological causes of hypersomnolence, the step-by-step diagnostic algorithms with the use of subjective evaluation tools and objective assessment, as well as management approaches.

This Research Topic will welcome any types of manuscripts supported by the Journal – comprised of research article, brief research article, review, and mini-review – pertaining, but not limited to the following themes:
• Diagnostics of hypersomnolence disorders
• Treatment of hypersomnolence disorders
• Neurobiological mechanisms of hypersomnolence disorders
• Experimental models of narcolepsy
• Epidemiology of hypersomnolence disorders

Conflicts of interest: Dr Korostovtseva receives a grant from the Russian Scientific Foundation. Dr. Sviryaev receives grants from the Russian Scientific Foundation and Russian Foundation of Fundamental Research. Additionally, Dr Deleanu is a partner at Somnolog Clinic.

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