About this Research Topic
This topic in Regulated and Non-Apoptotic Cell Death will publish high-quality review articles on all forms of non-apoptotic cell death including necroptosis, ferroptosis, parthanatos, pyroptosis, autophagic cell death, and their importance in development, physiology and diseases. It aims to highlight recent advances in the field, whilst emphasizing important directions and new possibilities for future inquiries.
Areas covered include:
• Dynamic of regulated cell death during differentiation and development.
• Central role mitochondria in regulated cell death (apoptosis excluded).
• Regulated necrosis and the associated anti-cancer immune response to overcome cancer resistance to apoptosis.
• Non-apoptotic death pathways and the contributions of neuron-glia communication and inflammation in neurodegeneration.
• Non-apoptotic functions of core apoptotic genes in cell differentiation, development, proliferation and apoptosis-induced proliferation.
• Mechanisms of crosstalks between cell death pathways, such as apoptosis and necrosis or between apoptosis and stress response pathways, including autophagy.
Studies focusing on the function of core apoptotic genes in the execution of apoptosis can be
submitted to our sister section ‘Apoptosis’.
The Reviews in Cell Death: Regulated and Non-Apoptotic Cell Death collection welcomes full-length, mini or systematic review papers. New articles will be added to this collection as they are published.
Keywords: Cell Death, Regulated, Non-Apoptotic, Mitochondria, Necrosis, Death Pathways, Functions, Mechanisms, Autophagy, Review Articles, Regulated Cell Death, Programmed Necrosis, Ferroptosis, Necroptosis, Pyroptosis
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.