About this Research Topic
This Research Topic will address the problem of lack of literature on modern and detailed drug discovery studies that demonstrates sources, protocols, techniques, and clinical observations to manage and potentially treat allergic diseases in the mouth, nostrils, lungs, and skin among others on the African continent.
Suitable themes include, but are not limited to:
- African anti-allergy natural products’ pharmacogenetic and botanical perspectives that include phytochemistry, taxonomy and conservation
- Pharmacology of allergies and anti-allergy drugs (conventional and natural products) on the African continent
- Development of datasets, databases, protocols, and codes (if applicable) related to anti-allergy drugs and allergies that can be used by other researchers
- Reproducible experiments confirming in-silico, in-vitro and/or in-vivo hits
- Medicinal chemistry studies of drugs against allergies and that causes allergies in Africa
- Chemical Biology and immunological studies in Africa on allergies and drugs against allergies
- Quantitative Structure-Activity Relationships (QSAR) of various African natural products with potential to manage or stop allergies
- Application of innovative and reproducible cheminformatics, bioinformatic and artificial intelligence methods for drug discovery against allergies in Africa including Structure- and Ligand-Based drug design among others
- Clinical observations and interventions to manage drug caused allergies and to manage allergies with drugs on the African continent
All article types accepted by Frontiers are accepted.
Conflict of interest declaration: Dr. Peter has received speakers fees, travel support for conference attendance from Takeda, CSL Behring, Pharming and Novartis as well as educational grants from Takeda and Novartis.
Keywords: Molecular Docking, Machine Learning, Natural products, H1-Receptors, Endothelial cells, Immunology, Respiratory epithelium, Inflammation, Antihistamines
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.