About this Research Topic
With this Research Topic, our goal is to collect original research articles and reviews focusing on metal ions in aging and neurodegeneration. The metal ions were shown to be involved in the process of aging and neurodegeneration, hence, the usage of metal chelators or drugs to combat aging and neurodegeneration via regulating metal ions homeostasis is an interesting topic. However, to date, the mechanisms of metal ions disorder in aging and neurodegeneration remain largely unknown, which greatly impedes the development of new drugs to relief aging and neurodegeneration.
This Topic welcomes submissions of original research, reviews, protocols, mini reviews, perspectives and brief research reports. Areas to be covered in this Research Topic may include, but are not limited to:
• Molecular mechanisms of metal ion disorder in aging or neurodegenerative brains
• Ferroptosis or cuproptosis during aging and neurodegeneration
• Actions of metal ions on neuroinflammation, oxidative stress and energy metabolism in brain
• Comparative studies of metal ions
• Development of drugs to regulating metal ions homeostasis in aging or neurodegenerative brains
• Interplay between peripheral metal ions disorder and brain aging
Keywords: metal ions, aging, neurodegeneration diseases, ferroptosis, cuproptosis
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.